製品の概要

  • 製品名Anti-ACAD8 antibody
    ACAD8 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ACAD8
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Cow
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 146-411 of Human ACAD8 (NP_055199).

  • ポジティブ・コントロール
    • 293T whole cell lysate

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab96567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 45 kDa.

ターゲット情報

  • 機能Has very high activity toward isobutyryl-CoA. Is an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Plays a role in transcriptional coactivation within the ARC complex.
  • 組織特異性Detected at comparable levels in all tissues examined (heart, lung, brain, skeletal muscle, pancreas and placenta). Weakly expressed in liver and kidney.
  • パスウェイAmino-acid degradation; L-valine degradation.
  • 関連疾患Defects in ACAD8 are the cause of isobutyryl-CoA dehydrogenase deficiency (IBDD) [MIM:611283]. The symptoms of IBDD generally appear until late in infancy or in childhood and can include poor feeding and growth (failure to thrive), a weakened and enlarged heart (dilated cardiomyopathy), seizures, and low numbers of red blood cells (anemia).
  • 配列類似性Belongs to the acyl-CoA dehydrogenase family.
  • 細胞内局在Mitochondrion.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ACAD 8 antibody
    • ACAD-8 antibody
    • ACAD8 antibody
    • ACAD8_HUMAN antibody
    • Activator-recruited cofactor 42 kDa component antibody
    • Acyl CoA dehydrogenase family member 8 antibody
    • Acyl Coenzyme A dehydrogenase family member 8 antibody
    • Acyl-CoA dehydrogenase family member 8 antibody
    • ARC42 antibody
    • FLJ22590 antibody
    • IBD antibody
    • Isobutyryl-CoA dehydrogenase antibody
    • Isobutyryl-CoA dehydrogenase, mitochondrial antibody
    • mitochondrial antibody
    see all

Anti-ACAD8 antibody 画像

  • Anti-ACAD8 antibody (ab96567) at 1/500 dilution + 293T whole cell lysate at 30 µg

    Predicted band size : 45 kDa

Anti-ACAD8 antibody (ab96567) 使用論文

ab96567 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab96567.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"