Ac-TVASSSTA Octapeptide peptide (ab95132)
Key features and details
- Purity: > 85% HPLC
- Suitable for: MS, Functional Studies
製品の詳細
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製品名
Ac-TVASSSTA Octapeptide peptide -
精製度
> 85 % HPLC. -
Animal free
No -
由来
Synthetic
特性
Our Abpromise guarantee covers the use of ab95132 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Mass Spectrometry
Functional Studies
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製品の状態
Lyophilized -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.40
Constituents: 2.38% HEPES, 0.58% Sodium chloride -
再構成Hydrate in 0.5ml of H2O.
関連情報
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関連性
Ac-TVASSSTA is an Octapeptide mimic of the N-terminal residues of the reactive center loop of PAI-1 (cf. P14-P7 residues). The Octapeptide inactivates PAI-1 by substituting for strand 4 in beta-sheet A in a manner that competes with formation of the latent species. Insertion of the peptide into beta-sheet A effectively forms a stable complex that converts PAI-1 into a substrate for tissue-type plasminogen activator (tPA) and other target proteinases. The resulting species of PAI-1 is thermodynamically stable and is useful for investigating the role of reactive center loop insertion.
画像
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Mass spectrometry analysis of ab95132
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HPLC analysis of ab95132
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10% SDS-PAGE Reduced
Lane 1: PAI-1 (5 ug) Frozen Lane 2: PAI-1 (5 ug) Incubated
Lane 3: PAI-1 (5 ug) + ab95132 (3 ug) Incubated Lane 4: PAI-1 (5 ug) Frozen + tPA (0.07 ug)
Lane 5: PAI-1 (5 ug) Incubated + tPA (0.07 ug) Lane 6: PAI-1 (5 ug) + ab95132 (3 ug) Incubated + tPA (0.07 ug)
Lane 7: Molecular weight markers
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab95132 は論文での使用が確認できていません。