製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to ABHD12
  • 特異性
    ab81906 is expected to recognize isoform a (NP_001035937.1) only.
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Rat
    交差が予測される動物種: Human, Cynomolgus monkey
  • 免疫原

    Synthetic peptide:

    C-REFLGKSEPEHQH

    , corresponding to C terminal amino acids 386-398 of Human ABHD12 (NP_001035937.1).

  • ポジティブ・コントロール
    • Mouse Brain and Rat Brain lysates.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    ab81906 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG

アプリケーション

Our Abpromise guarantee covers the use of ab81906 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報
    Peptide ELISA: Antibody detection limit dilution 1/32000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 45 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Has 2-arachidonoylglycerol hydrolase activity (By similarity). May be a regulator of endocannabinoid signaling pathways.
    • 関連疾患
      Defects in ABHD12 are the cause of polyneuropathy hearing loss ataxia retinitis pigmentosa and cataract (PHARC) [MIM:612674]. PHARC is a slowly progressive neurologic disorder with a variable phenotype resembling Refsum disease. Clinical features include sensorineural hearing loss, visual problems related to cataracts, retinitis pigmentosa, pes cavus, ataxic and/or spastic gait disturbances with a progressive sensorimotor peripheral neuropathy. Other features include hyporeflexia, hyperreflexia, extensor plantar responses.
    • 配列類似性
      Belongs to the serine esterase family.
    • 翻訳後修飾
      Glycosylated.
    • 細胞内局在
      Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 2-arachidonoylglycerol hydrolase antibody
      • 6330583M11Rik antibody
      • ABD12_HUMAN antibody
      • ABHD12 antibody
      • ABHD12A antibody
      • Abhydrolase domain containing protein 12 antibody
      • Abhydrolase domain-containing protein 12 antibody
      • AI431047 antibody
      • AW547313 antibody
      • BEM46L2 antibody
      • C20orf22 antibody
      • Monoacylglycerol lipase ABHD12 antibody
      • RP23-241M12.2 antibody
      see all

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    プロトコール

    参考文献

    ab81906 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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