製品の概要

  • 製品名
  • 製品の詳細
    Mouse polyclonal to ABHD12
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length Human protein (NP_056415.1, aa 1 to ~404)

  • ポジティブ・コントロール
    • ABHD12-transfected 293T cell lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度
    Protein A purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG

アプリケーション

Our Abpromise guarantee covers the use of ab68949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).

ターゲット情報

  • 機能
    Has 2-arachidonoylglycerol hydrolase activity (By similarity). May be a regulator of endocannabinoid signaling pathways.
  • 関連疾患
    Defects in ABHD12 are the cause of polyneuropathy hearing loss ataxia retinitis pigmentosa and cataract (PHARC) [MIM:612674]. PHARC is a slowly progressive neurologic disorder with a variable phenotype resembling Refsum disease. Clinical features include sensorineural hearing loss, visual problems related to cataracts, retinitis pigmentosa, pes cavus, ataxic and/or spastic gait disturbances with a progressive sensorimotor peripheral neuropathy. Other features include hyporeflexia, hyperreflexia, extensor plantar responses.
  • 配列類似性
    Belongs to the serine esterase family.
  • 翻訳後修飾
    Glycosylated.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 2-arachidonoylglycerol hydrolase antibody
    • 6330583M11Rik antibody
    • ABD12_HUMAN antibody
    • ABHD12 antibody
    • ABHD12A antibody
    • Abhydrolase domain containing protein 12 antibody
    • Abhydrolase domain-containing protein 12 antibody
    • AI431047 antibody
    • AW547313 antibody
    • BEM46L2 antibody
    • C20orf22 antibody
    • Monoacylglycerol lipase ABHD12 antibody
    • RP23-241M12.2 antibody
    see all

画像

  • All lanes : Anti-ABHD12 antibody (ab68949) at 1/500 dilution

    Lane 1 : ABHD12 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

    Predicted band size : 45 kDa
    Observed band size : 45 kDa

プロトコール

参考文献

This product has been referenced in:
  • Navia-Paldanius D  et al. Biochemical and pharmacological characterization of human a/ß-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12). J Lipid Res 53:2413-24 (2012). WB . Read more (PubMed: 22969151) »

See 1 Publication for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab68949.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録