製品の概要

  • 製品名Anti-ABCD1 antibody
    ABCD1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to ABCD1
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Horse, Dog
  • 免疫原

    Synthetic peptide:

    EDMQRKGYSEQD

    , corresponding to amino acids 564-575 of Human ABCD1 (NP_000024.2)

  • ポジティブ・コントロール
    • Human brain (cerebellum) lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab77364 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/32000.
    WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 83 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity.
    • 関連疾患Defects in ABCD1 are the cause of adrenoleukodystrophy X-linked (X-ALD) [MIM:300100]. X-ALD is a peroxisomal metabolic disorder characterized by progressive multifocal demyelination of the central nervous system and by peripheral adrenal insufficiency (Addison disease). It results in mental deterioration, corticospinal tract dysfunction, and cortical blindness. Different clinical manifestations exist like: cerebral childhood ALD (CALD), adult cerebral ALD (ACALD), adrenomyeloneuropathy (AMN) and 'Addison disease only' (ADO) phenotype.
      Note=The promoter region of ABCD1 is deleted in the chromosome Xq28 deletion syndrome which involves ABCD1 and the neighboring gene BCAP31.
    • 配列類似性Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
      Contains 1 ABC transmembrane type-1 domain.
      Contains 1 ABC transporter domain.
    • 細胞内局在Peroxisome membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • ABC42 antibody
      • Abcd1 antibody
      • ABCD1_HUMAN antibody
      • Adrenoleukodystrophy protein antibody
      • ALD antibody
      • Aldgh antibody
      • ALDP antibody
      • AMN antibody
      • ATP binding cassette, sub family D (ALD), member 1 antibody
      • ATP-binding cassette sub-family D member 1 antibody
      • OTTHUMP00000025960 antibody
      • OTTMUSP00000019283 antibody
      • RGD1562128 antibody
      • RP23 373N8.2 antibody
      • X linked adrenoleukodystrophy (ALD) gene homolog antibody
      see all

    Anti-ABCD1 antibody 画像

    • All lanes : Anti-ABCD1 antibody (ab77364) at 1 µg/ml

      Lane 1 : Cell lysate prepared from HEK293 mock transfected cells.
      Lane 2 : Cell lysate prepared from HEK293 cells overexpressing human ABCD1.


      Predicted band size : 83 kDa

    Anti-ABCD1 antibody (ab77364) 使用論文

    ab77364 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab77364.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"