製品の概要
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製品名Anti-ABCD1 antibody
ABCD1 一次抗体 製品一覧 -
製品の詳細Goat polyclonal to ABCD1
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由来種Goat
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アプリケーション適用あり: WB, ELISAmore details
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種交差性交差種: Human
交差が予測される動物種: Horse, Dog
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免疫原
Synthetic peptide:
EDMQRKGYSEQD
, corresponding to amino acids 564-575 of Human ABCD1 (NP_000024.2) -
ポジティブ･コントロール
- Human brain (cerebellum) lysates
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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バッファーPreservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3 -
Concentration information loading... -
精製度Immunogen affinity purified
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特記事項（精製）Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab77364 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | ||
| ELISA |
追加情報
Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/32000.
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 83 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 83 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity.
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関連疾患Defects in ABCD1 are the cause of adrenoleukodystrophy X-linked (X-ALD) [MIM:300100]. X-ALD is a peroxisomal metabolic disorder characterized by progressive multifocal demyelination of the central nervous system and by peripheral adrenal insufficiency (Addison disease). It results in mental deterioration, corticospinal tract dysfunction, and cortical blindness. Different clinical manifestations exist like: cerebral childhood ALD (CALD), adult cerebral ALD (ACALD), adrenomyeloneuropathy (AMN) and 'Addison disease only' (ADO) phenotype.
Note=The promoter region of ABCD1 is deleted in the chromosome Xq28 deletion syndrome which involves ABCD1 and the neighboring gene BCAP31. -
配列類似性Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
Contains 1 ABC transmembrane type-1 domain.
Contains 1 ABC transporter domain. -
細胞内局在Peroxisome membrane.
- Information by UniProt
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参照データベース
- Entrez Gene: 215 Human
- Omim: 300371 Human
- SwissProt: P33897 Human
- Unigene: 159546 Human
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別名
- ABC42 antibody
- Abcd1 antibody
- ABCD1_HUMAN antibody
see all
画像
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Western blot - Anti-ABCD1 antibody (ab77364)All lanes : Anti-ABCD1 antibody (ab77364) at 1 µg/ml
Lane 1 : Cell lysate prepared from HEK293 mock transfected cells.
Lane 2 : Cell lysate prepared from HEK293 cells overexpressing human ABCD1.
Predicted band size: 83 kDa
プロトコール
参考文献
ab77364 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"