製品の概要

  • 製品名Anti-ABCD1 antibody
    ABCD1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ABCD1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 264-293 of Human ABCD1 (NP_000024.2)

  • ポジティブ・コントロール
    • HL-60 cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab107094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 83 kDa.

ターゲット情報

  • 機能Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity.
  • 関連疾患Defects in ABCD1 are the cause of adrenoleukodystrophy X-linked (X-ALD) [MIM:300100]. X-ALD is a peroxisomal metabolic disorder characterized by progressive multifocal demyelination of the central nervous system and by peripheral adrenal insufficiency (Addison disease). It results in mental deterioration, corticospinal tract dysfunction, and cortical blindness. Different clinical manifestations exist like: cerebral childhood ALD (CALD), adult cerebral ALD (ACALD), adrenomyeloneuropathy (AMN) and 'Addison disease only' (ADO) phenotype.
    Note=The promoter region of ABCD1 is deleted in the chromosome Xq28 deletion syndrome which involves ABCD1 and the neighboring gene BCAP31.
  • 配列類似性Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
    Contains 1 ABC transmembrane type-1 domain.
    Contains 1 ABC transporter domain.
  • 細胞内局在Peroxisome membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ABC42 antibody
    • Abcd1 antibody
    • ABCD1_HUMAN antibody
    • Adrenoleukodystrophy protein antibody
    • ALD antibody
    • Aldgh antibody
    • ALDP antibody
    • AMN antibody
    • ATP binding cassette, sub family D (ALD), member 1 antibody
    • ATP-binding cassette sub-family D member 1 antibody
    • OTTHUMP00000025960 antibody
    • OTTMUSP00000019283 antibody
    • RGD1562128 antibody
    • RP23 373N8.2 antibody
    • X linked adrenoleukodystrophy (ALD) gene homolog antibody
    see all

Anti-ABCD1 antibody 画像

  • Anti-ABCD1 antibody (ab107094) at 1/100 dilution + HL-60 cell lysate at 35 µg

    Predicted band size : 83 kDa

Anti-ABCD1 antibody (ab107094) 使用論文

ab107094 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"