製品の概要

  • 製品名Anti-ABCC11 antibody
    ABCC11 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to ABCC11
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human, Chimpanzee, Rhesus monkey
  • 免疫原

    Recombinant fragment: FVPIAVKGLT NSKSAVMRFK KFFLQESPVF YVQTLQDPSK ALVFEEATLS WQQTCPGIVN GALELERNGH ASEGMTRPRD ALGPEEEGNS LGPELHKINL, corresponding to amino acids 433-533 of Human ABCC11 (NP_115972) with tag.

  • ポジティブ・コントロール
    • Recombinant tagged human ABCC11 fragment.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab76727 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
  • 追加情報ELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 154 kDa.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性ABCC11 belongs to the ABC transporter family, conjugate transporter (TC 3.A.1.208) subfamily. It contains two ABC transmembrane type-1 domains and two ABC transporter domains. ABCC11 participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides and enhances the cellular extrusion of cAMP and cGMP. It also stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. It probably functions to secrete earwax.
    • 細胞内局在Membrane; Multi-pass membrane protein.
    • 参照データベース
    • 別名
      • ABCC 11 antibody
      • ATP binding cassette protein C11 antibody
      • ATP binding cassette sub family C (CFTR/MRP) member 11 antibody
      • ATP binding cassette sub family C member 11 antibody
      • ATP binding cassette transporter MRP8 antibody
      • ATP binding cassette transporter sub family C member 11 antibody
      • EWWD antibody
      • MRP8 antibody
      • Multi resistance protein 8 antibody
      • Multidrug resistance associated protein 8 antibody
      • OTTHUMP00000164191 antibody
      • WW antibody
      see all

    Anti-ABCC11 antibody 画像

    • Anti-ABCC11 antibody (ab76727) at 1 µg/ml + Recombinant tagged human ABCC11 fragment at 0.1 µg

      Secondary
      Goat anti-mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

      Predicted band size : 154 kDa
      Observed band size : 37 kDa (why is the actual band size different from the predicted?)

    Anti-ABCC11 antibody (ab76727) 使用論文

    ab76727 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab76727.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"