Anti-ABCC10 抗体 (ab69296)
Key features and details
- Mouse polyclonal to ABCC10
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-ABCC10 antibody
ABCC10 一次抗体 製品一覧 -
製品の詳細
Mouse polyclonal to ABCC10 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein within Human ABCC10 aa 1-300. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
-
ポジティブ・コントロール
- ABCC10 transfected 293T cell lysate
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
-
精製度
Protein G purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab69296の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/500 - 1/1000. Detects a band of approximately 29 kDa (predicted molecular weight: 31 kDa).
|
特記事項 |
---|
WB
1/500 - 1/1000. Detects a band of approximately 29 kDa (predicted molecular weight: 31 kDa). |
ターゲット情報
-
機能
ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion. -
組織特異性
Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed. -
配列類似性
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains. -
細胞内局在
Cell membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 89845 Human
- Omim: 612509 Human
- SwissProt: Q5T3U5 Human
- Unigene: 55879 Human
-
別名
- ABCC10 antibody
- ATP binding cassette, sub family C (CFTR/MRP), member 10 antibody
- ATP binding cassette, subfamily C, member 10 antibody
see all
画像
-
All lanes : Anti-ABCC10 antibody (ab69296) at 1/500 dilution
Lane 1 : ABCC10 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 31 kDa
Observed band size: 29 kDa why is the actual band size different from the predicted?
データシートおよび資料
-
Datasheet download
参考文献 (4)
ab69296 は 4 報の論文で使用されています。
- Huang Y et al. SOX2 regulates paclitaxel resistance of A549 non‑small cell lung cancer cells via promoting transcription of ClC‑3. Oncol Rep 48:N/A (2022). PubMed: 36069232
- Takahashi M et al. Anti-TGF-β1 aptamer enhances therapeutic effect of tyrosine kinase inhibitor, gefitinib, on non-small cell lung cancer in xenograft model. Mol Ther Nucleic Acids 29:969-978 (2022). PubMed: 36189081
- Huang W et al. A Novel miR-98 Negatively Regulates the Resistance of Endometrial Cancer Cells to Paclitaxel by Suppressing ABCC10/MRP-7. Front Oncol 11:809410 (2021). PubMed: 34950596
- Ren YL & Zhang W Propofol promotes apoptosis of colorectal cancer cells via alleviating the suppression of lncRNA HOXA11-AS on miRNA let-7i. Biochem Cell Biol N/A:N/A (2019). PubMed: 31013434