製品の概要

  • 製品名Anti-ABCB7 antibody
    ABCB7 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ABCB7
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Rat, Human
  • 免疫原

    Synthetic peptide derived from within residues 100 - 200 of Human ABCB7.

    (Peptide available as ab66358.)

  • ポジティブ・コントロール
    • This antibody gave a positive signal in the following tissue lysates: Rat Thymus, Human Spinal Cord, Human Kidney, Human Liver.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab116606 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 83 kDa (predicted molecular weight: 83 kDa).Can be blocked with Human ABCB7 peptide (ab66358).

ターゲット情報

  • 機能Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
  • 関連疾患Defects in ABCB7 are the cause of X-linked sideroblastic anemia with ataxia (ASAT) [MIM:301310]. ASAT is a recessive disorder characterized by an infantile to early childhood onset of nonprogressive cerebellar ataxia and mild anemia with hypochromia and microcytosis.
  • 配列類似性Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
    Contains 1 ABC transmembrane type-1 domain.
    Contains 1 ABC transporter domain.
  • 細胞内局在Mitochondrion inner membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ABC transporter 7 protein antibody
    • ABC7 antibody
    • Abcb7 antibody
    • ABCB7_HUMAN antibody
    • ASAT antibody
    • Atm1p antibody
    • ATP binding cassette 7 antibody
    • ATP binding cassette sub family B (MDR/TAP) member 7 antibody
    • ATP binding cassette sub family B member 7 antibody
    • ATP binding cassette sub family B member 7 mitochondrial antibody
    • ATP binding cassette transporter 7 antibody
    • ATP-binding cassette sub-family B member 7 antibody
    • ATP-binding cassette transporter 7 antibody
    • EST140535 antibody
    • MDR7 antibody
    • mitochondrial antibody
    • Multidrug resistance protein 7 antibody
    • P-glycoprotein 7 antibody
    • PGP7 antibody
    see all

Anti-ABCB7 antibody 画像

  • All lanes : Anti-ABCB7 antibody (ab116606) at 1 µg/ml

    Lane 1 : Thymus (Rat) Tissue Lysate
    Lane 2 : Human spinal cord tissue lysate - total protein (ab29188)
    Lane 3 : Human kidney tissue lysate - total protein (ab30203)
    Lane 4 : Human liver tissue lysate - total protein (ab29889)

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 83 kDa
    Observed band size : 83 kDa


    Exposure time : 90 seconds

Anti-ABCB7 antibody (ab116606) 使用論文

ab116606 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"