Anti-BDP1 抗体 [2073D1a] (ab74415)
Key features and details
- Mouse monoclonal [2073D1a] to BDP1
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG1
製品の概要
-
製品名
Anti-BDP1 antibody [2073D1a] -
製品の詳細
Mouse monoclonal [2073D1a] to BDP1 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Recombinant fragment
交差が予測される動物種: Human -
免疫原
Recombinant fragment corresponding to Human BDP1 (internal sequence).
-
ポジティブ・コントロール
- Immunised BDP1 recombinant fragment.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 1% BSA, PBS -
Concentration information loading...
-
精製度
Protein G purified -
特記事項(精製)
ab74415 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum, and sterilised by filtration through a 0.22 µm membrane. -
ポリ/モノ
モノクローナル -
クローン名
2073D1a -
アイソタイプ
IgG1 -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab74415の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
Use at an assay dependent concentration. Predicted molecular weight: 294 kDa.
Please note that ab74415 has only been tested on the recombinant protein, not native Human samples. |
特記事項 |
---|
WB
Use at an assay dependent concentration. Predicted molecular weight: 294 kDa. Please note that ab74415 has only been tested on the recombinant protein, not native Human samples. |
ターゲット情報
-
関連性
TAF3B1 is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. It localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription. -
細胞内局在
Nuclear -
参照データベース
- Entrez Gene: 55814 Human
- Omim: 607012 Human
- SwissProt: A6H8Y1 Human
-
別名
- B double prime 1 subunit of RNA polymerase III transcription initiation factor IIIB antibody
- BDP 1 antibody
- BDP1 antibody
see all
画像
データシートおよび資料
-
Datasheet download
参考文献 (1)
ab74415 は 1 報の論文で使用されています。
- Girotto G et al. Linkage study and exome sequencing identify a BDP1 mutation associated with hereditary hearing loss. PLoS One 8:e80323 (2013). IHC-P ; Mouse . PubMed: 24312468