L-AP4 (mM/ml), group III mGlu agonist (ab144481)
Key features and details
- Selective group III mGlu agonist. 1 ml water soluble pack.
- CAS Number: 23052-81-5
- Purity: > 99%
- Soluble in 1 ml water to give specified mM/ml concentration
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
L-AP4 (mM/ml), group III mGlu agonist -
製品の詳細
Selective group III mGlu agonist. 1 ml water soluble pack. -
生理活性の詳細
Selective group III mGlu agonist.
Soluble in 1 ml water to give specified mM/ml concentration. Find out more. -
精製度
> 99% -
CAS 番号
23052-81-5 -
構造式
製品の特性
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体系名
L-(+)-2-Amino-4-phosphonobutyric acid -
分子量
183.10 -
分子式
C4H10NO5P -
PubChem 登録番号
179394 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in 1 ml water to give specified mM/ml concentration -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Add 1 ml of water to get an exact ready to use concentration.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
N[C@@H](CCP(=O)(O)O)C(=O)O -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (13)
ab144481 は 13 報の論文で使用されています。
- Buldyrev I & Taylor WR Inhibitory mechanisms that generate centre and surround properties in ON and OFF brisk-sustained ganglion cells in the rabbit retina. J Physiol 591:303-25 (2013). PubMed: 23045347
- Kalinichev M et al. ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization. J Pharmacol Exp Ther 344:624-36 (2013). PubMed: 23257312
- Goudet C et al. A novel selective metabotropic glutamate receptor 4 agonist reveals new possibilities for developing subtype selective ligands with therapeutic potential. FASEB J 26:1682-93 (2012). PubMed: 22223752
- Klyuch BP et al. Deletion of ecto-5'-nucleotidase (CD73) reveals direct action potential-dependent adenosine release. J Neurosci 32:3842-7 (2012). PubMed: 22423104
- Gosnell HB et al. mGluR8 modulates excitatory transmission in the bed nucleus of the stria terminalis in a stress-dependent manner. Neuropsychopharmacology 36:1599-607 (2011). PubMed: 21451497