Sulindac sulfide, COX-1 and 2 inhibitor (ab120650)
Key features and details
- Active metabolite of Sulindac. COX-1 and 2 inhibitor.
- CAS Number: 32004-67-4
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Sulindac sulfide, COX-1 and 2 inhibitor -
製品の詳細
Active metabolite of Sulindac. COX-1 and 2 inhibitor. -
生理活性の詳細
Cell-permeable, active metabolite of Sulindac. Inhibits Ras-induced malignant transformation and Ras/Raf-dependent transactivation. COX-1 and 2 inhibitor (Ki values are 1.02 and 10.43 μM, respectively). Additionally, inhibits γ-secretase. Apoptosis inducer.
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精製度
> 98% -
CAS 番号
32004-67-4 -
構造式
製品の特性
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体系名
(Z)-5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic acid -
分子量
340.41 -
分子式
C20H17FO2S -
保存方法
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (0)
ab120650 は論文での使用が確認できていません。