(S)-Sulpiride, D2-like dopamine antagonist (ab120579)
Key features and details
- D2-like dopamine antagonist. Active enantiomer.
- CAS Number: 23672-07-3
- Soluble in DMSO to 100 mM and in ethanol to 25 mM (with warming)
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
(S)-Sulpiride, D2-like dopamine antagonist -
製品の詳細
D2-like dopamine antagonist. Active enantiomer. -
生理活性の詳細
Selective D2-like dopamine antagonist (Ki values are ~ 0.015, ~ 0.013, and 1 μM at D2, D3, and D4 receptors, respectively). Active enantiomer of Sulpiride (ab120578). Antipsychotic and prokinetic agent.
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CAS 番号
23672-07-3 -
構造式
製品の特性
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体系名
(S)-(-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide -
分子量
341.42 -
分子式
C15H23N3O4S -
保存方法
Store at +4°C. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM and in ethanol to 25 mM (with warming) -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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由来
Synthetic
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研究分野
関連製品
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プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (1)
ab120579 は 1 報の論文で使用されています。
- Nimitvilai S et al. Effects of monoamines on the intrinsic excitability of lateral orbitofrontal cortex neurons in alcohol-dependent and non-dependent female mice. Neuropharmacology 137:1-12 (2018). PubMed: 29689260