製品の概要

  • 製品名Anti-A2ML1 antibody
  • 製品の詳細
    Mouse polyclonal to A2ML1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-158 of Human A2ML1

  • ポジティブ・コントロール
    • A2ML1 transfected 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab72872 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500. Predicted molecular weight: 18 kDa.

ターゲット情報

  • 関連性A2ML1 is a new member of the alpha 2-macroglobulin protease inhibitor family, and shares most the characteristics of this family. It is the first family member detected in the epidermis and may play an important role during desquamation by inhibiting extracellular proteases. The alpha-macroglobulin (AM) superfamily of proteins contains both complement components and protease inhibitors, including A2M and A2ML1. AM proteins display a unique trap mechanism of inhibition, by which the AM inhibitor undergoes a major conformational change upon its cleavage by a protease, thus trapping the protease and blocking it from subsequent substrate binding.
  • 細胞内局在Secreted
  • 参照データベース
  • 別名
    • A2ML 1 antibody
    • Alpha 2 macroglobulin like 1 antibody
    • Alpha 2 macroglobulin like protein 1 antibody
    • C3 and PZP like alpha 2 macroglobulin domain containing protein 9 antibody
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    • DKFZp686G1812 antibody
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    • DKFZp686O1010 antibody
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Anti-A2ML1 antibody 画像

  • All lanes : Anti-A2ML1 antibody (ab72872) at 1/500 dilution

    Lane 1 : A2ML1 transfected 293T cell lysate
    Lane 2 : non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 18 kDa
    Observed band size : 20 kDa (why is the actual band size different from the predicted?)

Anti-A2ML1 antibody (ab72872) 使用論文

This product has been referenced in:
  • Burgener A  et al. A systems biology examination of the human female genital tract shows compartmentalization of immune factor expression. J Virol 87:5141-50 (2013). Human . Read more (PubMed: 23449785) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"