Anti-Wnt1 抗体 (ab63934)
Key features and details
- Rabbit polyclonal to Wnt1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Wnt1 antibody
Wnt1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Wnt1 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide surrounding amino acid 31 of human Wnt1
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ポジティブ・コントロール
- WB: Jurkat cell lysate.
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特記事項
This product is manufactured by BioVision, an Abcam company and was previously called 3571 Anti-Wnt-1 Antibody. 3571-100 is the same size as the 100 µg size of ab63934.
Wnt1 antibody has been purified by Protein A/G combination.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: PBS, 30% Glycerol (glycerin, glycerine), 0.5% BSA -
Concentration information loading...
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ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab63934の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 0.5 - 4 µg/ml. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).
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特記事項 |
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WB
Use a concentration of 0.5 - 4 µg/ml. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa). |
ターゲット情報
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機能
Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. -
配列類似性
Belongs to the Wnt family. -
細胞内局在
Secreted > extracellular space > extracellular matrix. - Information by UniProt
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参照データベース
- Entrez Gene: 7471 Human
- Omim: 164820 Human
- SwissProt: P04628 Human
- Unigene: 248164 Human
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別名
- BMND16 antibody
- INT1 antibody
- OI15 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (6)
ab63934 は 6 報の論文で使用されています。
- Marcogliese PC et al. Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling. Sci Adv 8:eabl5613 (2022). PubMed: 35044823
- Jiang H et al. lncRNAS56464.1 as a ceRNA promotes the proliferation of fibroblast-like synoviocytes in experimental arthritis via the Wnt signaling pathway and sponges miR-152-3p. Int J Mol Med 47:N/A (2021). PubMed: 33448322
- Ortega MA et al. Abnormal proinflammatory and stressor environmental with increased the regulatory cellular IGF-1/PAPP-A/STC and Wnt-1/β-Catenin canonical pathway in placenta of women with Chronic venous Disease during Pregnancy. Int J Med Sci 18:2814-2827 (2021). PubMed: 34220309
- Chen L et al. Role of lncRNA BCYRN1 in trophoblast cell physiology and pathogenesis of preeclampsia. Exp Ther Med 22:1137 (2021). PubMed: 34466147
- Liu MM et al. Therapeutic potential of Liuwei Dihuang pill against KDM7A and Wnt/ß-catenin signaling pathway in diabetic nephropathy-related osteoporosis. Biosci Rep 40:N/A (2020). PubMed: 32914833
- Kim NH et al. p53 and microRNA-34 are suppressors of canonical Wnt signaling. Sci Signal 4:ra71 (2011). WB . PubMed: 22045851