Veratridine, Na+ channel opener (ab120279)
Key features and details
- Na+ channel opener
- CAS Number: 71-62-5
- Soluble in ethanol to 100 mM
- Form / State: Solid
- Source: Liliaceae sp.
製品の概要
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製品名
Veratridine, Na+ channel opener -
製品の詳細
Na+ channel opener -
CAS 番号
71-62-5 -
構造式
製品の特性
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体系名
3-Veratroylveracevine -
分子量
673.80 -
分子式
C36H51NO11 -
PubChem 登録番号
6610253 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in ethanol to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
COc1ccc(cc1OC)C(=O)OC4CC[C@@]7(C)C5CCC6[C@]8(O)C[C@H](O)[C@@]3(O)C(CN2CC(C)CCC2[C@@]3(C)O)[C@]8(O)C[C@@]67O[C@]45O -
由来
Liliaceae sp.
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (6)
ab120279 は 6 報の論文で使用されています。
- Wei XP et al. A novel reticular node in the brainstem synchronizes neonatal mouse crying with breathing. Neuron 110:644-657.e6 (2022). PubMed: 34998469
- Mohammed ZA et al. An unbiased and efficient assessment of excitability of sensory neurons for analgesic drug discovery. Pain 161:1100-1108 (2020). PubMed: 31929383
- Sousa SR et al. Discovery and mode of action of a novel analgesic ß-toxin from the African spider Ceratogyrus darlingi. PLoS One 12:e0182848 (2017). PubMed: 28880874
- Mohammed ZA et al. Veratridine produces distinct calcium response profiles in mouse Dorsal Root Ganglia neurons. Sci Rep 7:45221 (2017). PubMed: 28338073
- Henriques ST et al. Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7. J Biol Chem 291:17049-65 (2016). PubMed: 27311819
- Zimmermann K et al. Analgesic treatment of ciguatoxin-induced cold allodynia. Pain 154:1999-2006 (2013). PubMed: 23778293