Anti-ULK2 抗体 (ab97695)
Key features and details
- Rabbit polyclonal to ULK2
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-ULK2 antibody -
製品の詳細
Rabbit polyclonal to ULK2 -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICC/IFmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse -
免疫原
Recombinant protein fragment containing a sequence corresponding to a region within amino acids 693 and 938 of Human ULK2 (NP_055498).
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ポジティブ・コントロール
- 293T, H1299, HeLa, Molt-4, Raji cell lysates. HepG2 whole cell lysates. HeLa cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab97695の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
1/500 - 1/3000. Predicted molecular weight: 113 kDa.
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ICC/IF |
1/100 - 1/200.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 113 kDa. |
ICC/IF
1/100 - 1/200. |
ターゲット情報
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配列類似性
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
Contains 1 protein kinase domain. -
翻訳後修飾
Autophosphorylated. - Information by UniProt
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参照データベース
- Entrez Gene: 9706 Human
- Entrez Gene: 29869 Mouse
- Omim: 608650 Human
- SwissProt: Q8IYT8 Human
- SwissProt: Q9QY01 Mouse
- Unigene: 168762 Human
- Unigene: 162025 Mouse
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別名
- ATG1B antibody
- KIAA0623 antibody
- Serine/threonine protein kinase ULK2 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (8)
ab97695 は 8 報の論文で使用されています。
- Li J et al. Oxygen-sensitive methylation of ULK1 is required for hypoxia-induced autophagy. Nat Commun 13:1172 (2022). PubMed: 35246531
- Wang J et al. LncRNA GAS5 Suppressed Proliferation and Promoted Apoptosis in Laryngeal Squamous Cell Carcinoma by Targeting MiR-26a-5p and Modifying ULK2. Cancer Manag Res 13:871-887 (2021). PubMed: 33551645
- Schmitz K et al. An essential role of the autophagy activating kinase ULK1 in snRNP biogenesis. Nucleic Acids Res 49:6437-6455 (2021). PubMed: 34096600
- Li G et al. Long non-coding RNA growth arrest-specific 5 (GAS5) acts as a tumor suppressor by promoting autophagy in breast cancer. Mol Med Rep 22:2460-2468 (2020). PubMed: 32705220
- Corona Velazquez A et al. Poliovirus induces autophagic signaling independent of the ULK1 complex. Autophagy 14:1201-1213 (2018). PubMed: 29929428
- Blessing AM et al. Transcriptional regulation of core autophagy and lysosomal genes by the androgen receptor promotes prostate cancer progression. Autophagy 13:506-521 (2017). PubMed: 27977328
- Puto LA et al. Transcriptional Repressor DAXX Promotes Prostate Cancer Tumorigenicity via Suppression of Autophagy. J Biol Chem 290:15406-20 (2015). WB ; Human . PubMed: 25903140
- Konno H et al. Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling. Cell 155:688-98 (2013). PubMed: 24119841