Anti-Tropomodulin 2 抗体 (ab67407)
Key features and details
- Mouse polyclonal to Tropomodulin 2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Tropomodulin 2 antibody
Tropomodulin 2 一次抗体 製品一覧 -
製品の詳細
Mouse polyclonal to Tropomodulin 2 -
由来種
Mouse -
特異性
ab67407 is reactive against mammalian transfected lysate -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein within Human Tropomodulin 2 aa 1-400. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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ポジティブ・コントロール
- ICC: Murine Neuroblastoma (N1E-115) cells. WB: Tropomodulin 2 transfected 293T lysate, N1E-115 mouse neuroblastoma.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.4
Constituent: PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab67407の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (2) |
1/500 - 1/1000. Detects a band of approximately 39.6 kDa.
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特記事項 |
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WB
1/500 - 1/1000. Detects a band of approximately 39.6 kDa. |
ターゲット情報
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関連性
Tropomodulin is the actin-capping protein for the slow growing end of filamentous actin. Tropomodulin 2 is a neuronal specific isoform which is the major binding protein to brain tropomyosin in rat. -
細胞内局在
Cytoplasm; cytoskeleton -
参照データベース
- Entrez Gene: 29767 Human
- Omim: 602928 Human
- SwissProt: Q9NZR1 Human
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別名
- Tropomodulin 2 antibody
- MGC39481 antibody
- N Tmod antibody
see all
画像
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All lanes : Anti-Tropomodulin 2 antibody (ab67407) at 1/500 dilution
Lane 1 : Tropomodulin 2 transfected 293T lysate
Lane 2 : Non transfected 293T lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Observed band size: 39.6 kDa why is the actual band size different from the predicted? -
Lane 1 : Anti-Tropomodulin 2 antibody (ab67407) at 1/1000 dilution
Lane 2 : Anti-Tropomodulin 2 antibody [EPR6353] (ab124833) at 1/1000 dilution
All lanes : N1E-115 mouse neuroblastoma
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : Polyclonal HRP conjugate at 1/5000 dilution
データシートおよび資料
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Datasheet download
参考文献 (4)
ab67407 は 4 報の論文で使用されています。
- Omotade OF et al. Tropomodulin Isoform-Specific Regulation of Dendrite Development and Synapse Formation. J Neurosci 38:10271-10285 (2018). PubMed: 30301754
- Gu QH et al. miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement. Nat Commun 6:6789 (2015). PubMed: 25858512
- Hu Z et al. miR-191 and miR-135 are required for long-lasting spine remodelling associated with synaptic long-term depression. Nat Commun 5:3263 (2014). WB, ICC/IF . PubMed: 24535612
- Sun Y et al. A gel-based proteomic method reveals several protein pathway abnormalities in fetal Down syndrome brain. J Proteomics 74:547-57 (2011). WB ; Human . PubMed: 21262400