Thioridazine hydrochloride, Dopamine receptor antagonist (ab120580)
Key features and details
- Dopamine receptor antagonist
- CAS Number: 130-61-0
- Soluble in water to 100 mM, in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Thioridazine hydrochloride, Dopamine receptor antagonist -
製品の詳細
Dopamine receptor antagonist -
別名
- THIO
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生理活性の詳細
Dopamine receptor antagonist (Ki values are 16 (D2), 10 (D1), 7.8 (D3), and 31 (D4) nM). Also inhibits CYP2D6 (IC50 = 2.7 μM). Antipsychotic. Displays antituberculosis/ drug-resistant tuberculosis properties.
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CAS 番号
130-61-0 -
構造式
製品の特性
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体系名
10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride -
分子量
407.03 -
分子式
C21H26N2S2.HCl -
PubChem 登録番号
66062 -
保存方法
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 100 mM, in ethanol to 100 mM and in DMSO to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
Cl.CN4CCCCC4CCN1c3ccccc3Sc2ccc(SC)cc12 -
由来
Synthetic
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研究分野
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Retinoic & Retinoid
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Orphan Nuclear Receptors
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
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プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (0)
ab120580 は論文での使用が確認できていません。