Anti-TSH 抗体 (ab64378)
Key features and details
- Rabbit polyclonal to TSH
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-TSH antibody -
製品の詳細
Rabbit polyclonal to TSH -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Full length native protein (purified) corresponding to Human TSH.
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ポジティブ・コントロール
- Human anterior pituitary tissue
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特記事項
Cytoplasmic staining pattern
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab64378の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/200.
|
特記事項 |
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IHC-P
1/200. |
ターゲット情報
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関連性
Thyroid stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity. -
細胞内局在
Secreted -
参照データベース
- Entrez Gene: 1081 Human
- Entrez Gene: 7252 Human
- Omim: 118850 Human
- Omim: 188540 Human
- SwissProt: P01215 Human
- SwissProt: P01222 Human
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別名
- CG ALPHA antibody
- CGA antibody
- Chorionic gonadotropin alpha polypeptide antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab64378 は 1 報の論文で使用されています。
- Mathioudakis N et al. Expression of the pituitary stem/progenitor marker GFRa2 in human pituitary adenomas and normal pituitary. Pituitary 18:31-41 (2015). PubMed: 24402129