|
|
|
|
Western blot - TROY antibody (ab12126)
(enlarge)
|
|
|
|
|
Product Name
|
TROY antibody
|
| |
TROY 抗体 (3件) 一覧
|
|
Product type
|
Primary antibodies
|
|
Description
|
Rabbit polyclonal to TROY
|
|
Immunogen
|
Synthetic peptide, corresponding to amino acids 29-44, 204-219, and 409-421 of Human TROY.
|
|
Reacts with
(species key)
|
Hu, Ms
|
|
Specificity
|
ab12126 reacts with TROY.
|
|
Tested applications
(see key)
|
WB
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
WB: Use at a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 50.8 kDa). For optimal results, primary antibody incubations should be performed at room temperature.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Positive control
(see definition)
|
T98G cell extracts.
|
|
Cellular localization
|
Type I membrane protein (Probable).
|
|
Research areas
|
Cancer >> Growth factors >> TNF
Signal Transduction >> Growth Factors/Hormones >> TNF
Cell Biology >> Apoptosis >> Extracellular Signals >> Death Ligands
|
|
Relevance
|
TROY is a member of the TNF receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate the JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.
|
|
|
TROY antibody (ab12126)の別名 |
|
Database links
|
The links below go to external sites and will open in a new browser window |
|
Raised in
|
Rabbit
|
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Purity
|
Protein A purified
|
|
Storage buffer
|
Preservative: 0.02% Sodium Azide
Constituents: PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
|
|
Purification notes
|
Affinity purified.
|
|
Form
|
Liquid
|
|
Concentration
|
0.500 mg/ml
|
|
Storage instructions
|
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
|
| |
Abcam では全ての製品情報を一元管理しており、 TROY antibody について私たちが知りうる全ての情報がこのデータシートでご覧いただけます。ご不明な点がありましたら、 お問い合わせください。 |
 |
|
|
See below for TROY antibody images, references, products related to ab12126 and other tools.
|
| |
TROY antibody images:
|
 Western blot - TROY antibody (ab12126)
Predicted band size : 50.8 kDa
TROY detection by Western blot. The analysis of human TROY using this antibody in T98G, a human glioblastoma cell line extract. A protein band of approximately 46 kDa should be detected.
|
| |
References for TROY antibody (ab12126)
|
|
This product has been used in:
Wang Y et al. Targeted proteasome inhibition by Velcade induces apoptosis in human mesothelioma and breast cancer cell lines. Cancer Chemother Pharmacol 66:455-66 (2010). WB; Human. PubMed: 19960346
If you publish research using ab12126 please let us know so that we can cite the reference on this datasheet.
|
| |
|
Search PubMed (MEDLINE) for references to TROY
|
| |
TROY antibody - more information
|
Customer reviews (feedback) regarding TROY antibody |
Customer FAQs regarding TROY antibody |
Protocols for TROY antibody |
Price and availability of products related to TROY antibody |
| |
TROY antibody - related products:
|
|
|
| |
TROY antibody - other tools:
|
Contact Abcam with a Technical Enquiry about TROY antibody |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
