Anti-TRAF6BP/TAX1BP1 抗体 (ab121812)
Key features and details
- Rabbit polyclonal to TRAF6BP/TAX1BP1
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-TRAF6BP/TAX1BP1 antibody
TRAF6BP/TAX1BP1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to TRAF6BP/TAX1BP1 -
由来種
Rabbit -
アプリケーション
適用あり: ICC/IF, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment corresponding to Human TRAF6BP/TAX1BP1 aa 406-540.
Database link: Q86VP1 -
ポジティブ・コントロール
- IHC-P: Human testis, prostate and placenta tissue ICC/IF: U-2 OS cells
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab121812の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
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IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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特記事項 |
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ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. -
組織特異性
Expressed in all tissues tested. - Information by UniProt
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参照データベース
- Entrez Gene: 8887 Human
- Omim: 605326 Human
- SwissProt: Q86VP1 Human
- Unigene: 34576 Human
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別名
- 1200003J11Rik antibody
- 1700069J21Rik antibody
- Aa1076 antibody
see all
画像
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Immunofluorescent staining of Human cell line U-2 OS shows positivity in cytoplasm. Recommended concentration of ab121812 1-4 µg/ml. Cells treated with PFA/Triton X-100.
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Immunohistochemical analysis of human testis tissue labeling TRAF6BP/TAX1BP1 with ab121812 at 1/50 dilution.
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Immunohistochemical analysis of human prostate tissue labeling TRAF6BP/TAX1BP1 with ab121812 at 1/50 dilution.
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Immunohistochemical analysis of human placenta tissue labeling TRAF6BP/TAX1BP1 with ab121812 at 1/50 dilution.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab121812 は 1 報の論文で使用されています。
- Hernandez D et al. Interferon-Inducible E3 Ligase RNF213 Facilitates Host-Protective Linear and K63-Linked Ubiquitylation of Toxoplasma gondii Parasitophorous Vacuoles. mBio 13:e0188822 (2022). PubMed: 36154443