Anti-TMEM70 抗体 (ab106654)
Key features and details
- Rabbit polyclonal to TMEM70
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-TMEM70 antibody -
製品の詳細
Rabbit polyclonal to TMEM70 -
由来種
Rabbit -
特異性
Two isoforms of TMEM70 are known to exist; ab106654 will only recognize Isoform 1. ab106654 is predicted not to cross-react with other TMEM proteins. -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human TMEM70 (internal sequence). The immunogen is located within amino acids 150 - 200 (14 amino acid synthetic peptide) of TMEM70.
Database link: Q9BUB7 -
ポジティブ・コントロール
- WB: Human liver tissue lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106654の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-P |
Use a concentration of 5 µg/ml.
Validated in rat samples only. |
|
WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 29 kDa.
Validated in human samples only. |
|
IF |
Use a concentration of 20 µg/ml.
Validated in rat samples only. |
特記事項 |
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IHC-P
Use a concentration of 5 µg/ml. Validated in rat samples only. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 29 kDa. Validated in human samples only. |
IF
Use a concentration of 20 µg/ml. Validated in rat samples only. |
ターゲット情報
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機能
Involved in biogenesis of mitochondrial ATP synthase. -
関連疾患
Defects in TMEM70 are a cause of mitochondrial encephalocardiomyopathy neonatal due to ATP synthase deficiency (MT-ATPSD) [MIM:604273]; also known as ATPase deficiency. A mitochondrial disorder with heterogeneous clinical manifestations including dysmorphic features, psychomotor retardation, hypotonia, growth retardation, cardiomyopathy, enlarged liver, hypoplastic kidneys and elevated lactate levels in urine, plasma and cerebrospinal fluid. -
配列類似性
Belongs to the TMEM70 family. -
細胞内局在
Mitochondrion inner membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 54968 Human
- Omim: 612418 Human
- SwissProt: Q9BUB7 Human
- Unigene: 106650 Human
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別名
- FLJ20533 antibody
- MC5DN2 antibody
- OTTHUMP00000226855 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab106654 は 2 報の論文で使用されています。
- Du L et al. IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties. Cell Metab 29:1363-1375.e8 (2019). PubMed: 30745181
- de Souza AP et al. Gender-specific effects of intrauterine growth restriction on the adipose tissue of adult rats: a proteomic approach. Proteome Sci 13:32 (2015). PubMed: 26633942