Anti-Sla 抗体 (ab96620)
Key features and details
- Rabbit polyclonal to Sla
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Sla antibody -
製品の詳細
Rabbit polyclonal to Sla -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow -
免疫原
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ・コントロール
- 293T and A431 cell lysates
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab96620の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 31 kDa.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 31 kDa. |
ターゲット情報
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機能
Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. -
組織特異性
Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas. -
配列類似性
Contains 1 SH2 domain.
Contains 1 SH3 domain. -
ドメイン
The C-terminal domain is essential for the homodimerization and the interaction with CBL. While the interaction with CBL is apparently mediated via the hydrophobic region of this domain, the highly charged region is apparently required for the homodimerization. -
細胞内局在
Cytoplasm. Endosome. Colocalizes with endosomes. - Information by UniProt
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参照データベース
- Entrez Gene: 6503 Human
- Entrez Gene: 20491 Mouse
- Entrez Gene: 338477 Rat
- Omim: 601099 Human
- SwissProt: Q13239 Human
- SwissProt: Q60898 Mouse
- SwissProt: P59622 Rat
- Unigene: 75367 Human
see all -
別名
- hSLAP antibody
- SLA 1 antibody
- sla antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab96620 は論文での使用が確認できていません。