Anti-Serum Amyloid P 抗体 (ab17872)

製品の概要

  • 製品名
    Anti-Serum Amyloid P antibody
    Serum Amyloid P 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Serum Amyloid P
  • 特異性
    Specific for human SAP with no crossreactivity with CRP or other pentraxins.
  • アプリケーション
    適用あり: WB, ELISA, Sandwich ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Full length native protein (purified) (Human).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab17872 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/250 - 1/2500. Predicted molecular weight: 26.76 kDa.
ELISA 1/2500 - 1/10000.
Sandwich ELISA Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal [14B4] to Serum Amyloid P (ab27313). Use as detection antibody with recommended pair. See Abreview submitted by Jennifer Webster for details.

ターゲット情報

  • 機能
    Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
  • 組織特異性
    Found in serum and urine.
  • 関連疾患
    Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.
  • 配列類似性
    Belongs to the pentaxin family.
    Contains 1 pentaxin domain.
  • 翻訳後修飾
    N-glycosylated with a complex biantennary oligosaccharide chain with a sialic acid at the end (disialo-SAP). Monosialo-SAP as well as asioalo-SAP are also detected (PubMed:15174148).
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 9.5S alpha 1 glycoprotein antibody
    • 9.5S alpha-1-glycoprotein antibody
    • Amyloid P component serum antibody
    • APCS antibody
    • MGC88159 antibody
    • Pentaxin related antibody
    • Pentraxin 2 antibody
    • PTX 2 antibody
    • PTX2 antibody
    • SAMP_HUMAN antibody
    • SAP antibody
    • Serum amyloid P component antibody
    • Serum amyloid P-component(1-203) antibody
    see all

プロトコール

参考文献

ab17872 has not yet been referenced specifically in any publications.

レビューと Q&A

The reason why the customer is not seeing any bands is that normal brain has very very little SAP protein, therefore it is not surprising that the customer still sees no band. The reference below should be very useful, in particular, figure 3, whic...

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As Serum Amyloid P protein is only expressed in high levels in AD patients as is in low levels in normal subjects I think the problem is therefore low levels in the samples. Furthermore, the customer should try incubating in more concentrated antibo...

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Thank you for contacting us for technical support on behalf of your customer. Many thanks for providing so much protocol information and the images of the blot. It enabled me to understand the problem very easily and rapidly. I am a little confused...

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application
ELISA
Sample
Human Serum (Serum)
Specification
Serum
Blocking step
BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5%
Type
Sandwich
Username

Miss. Jennifer Webster

Verified customer

投稿 Aug 16 2006

Good morning, Unfortunately the source of ab17872 does not have an image of the western blot to provide us. I am very sorry for this inconvenience, Best of luck with your research,

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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