Anti-Serotonin 抗体 (ab66047)
Key features and details
- Goat polyclonal to Serotonin
- Suitable for: IHC-FoFr
- Reacts with: Species independent
- Isotype: IgG
製品の概要
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製品名
Anti-Serotonin antibody
Serotonin 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to Serotonin -
由来種
Goat -
アプリケーション
適用あり: IHC-FoFrmore details -
種交差性
交差種: Species independent -
免疫原
Serotonin whole molecule conjugated to BSA with paraformaldehyde.
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特記事項
If the product is lyophilized upon delivery, dilute with phosphate buffer or Tris buffer at dilutions no higher than 1/10, aliquot and freeze at -15° C or lower. Antibody can be stored for up to six months if handled as described above.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Constituent: Whole serum -
Concentration information loading...
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精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab66047の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-FoFr |
1/400 - 1/800. When using Biotin/Streptavidin-HRP Technique dilution of 1/5000 - 1/10000.
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特記事項 |
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IHC-FoFr
1/400 - 1/800. When using Biotin/Streptavidin-HRP Technique dilution of 1/5000 - 1/10000. |
ターゲット情報
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関連性
Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesised in serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin plays an important part in the biochemistry of depression, migraine, bipolar disorder and anxiety. It is also believed to be influential on sexuality and appetite. 5-HT is generally thought not to be released from synaptic terminal buttons in the manner of classical neurotransmission but from serotonergic varacosities into the extra neuronal space. From here it is free to diffuse over a relatively large region of space (>20µm) and activate 5-HT receptors located on the dendrites, cell bodies and presynaptic terminals of adjacent neurons. Serotonergic action is terminated primarily via uptake of 5-HT from the synapse. This is through the specific monoamine transporter for 5-HT, 5-HT reuptake transporter, on the presynaptic neuron. The pharmacology of 5-HT is extremely complex, with its actions being mediated by a large and diverse range of 5-HT receptors. -
細胞内局在
Cytoplasmic and Secreted -
別名
- 5 hydroxytryptamine antibody
- 5HT antibody
画像
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ab66407 staining of rat hypothalamus using 4+ biotin-streptavidin/HRP staing at 1/4000.
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (59)
ab66047 は 59 報の論文で使用されています。
- Widmayer P et al. Short-term high fat feeding induces inflammatory responses of tuft cells and mucosal barrier cells in the murine stomach. Histol Histopathol 38:273-286 (2023). PubMed: 35904321
- Riemens RJM et al. Targeted Methylation Profiling of Single Laser-Capture Microdissected Post-Mortem Brain Cells by Adapted Limiting Dilution Bisulfite Pyrosequencing (LDBSP). Int J Mol Sci 23:N/A (2022). PubMed: 36555213
- Xu T et al. Multiple therapeutic effects of human neural stem cells derived from induced pluripotent stem cells in a rat model of post-traumatic syringomyelia. EBioMedicine 77:103882 (2022). PubMed: 35182996
- Kabdesh IM et al. Cellular and Molecular Gradients in the Ventral Horns With Increasing Distance From the Injury Site After Spinal Cord Contusion. Front Cell Neurosci 16:817752 (2022). PubMed: 35221924
- Chen Z et al. Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis. Immunity 54:151-163.e6 (2021). PubMed: 33220232