Anti-SOX22 抗体 [86C2a] (ab54371)
Key features and details
- Mouse monoclonal [86C2a] to SOX22
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG2a
製品の概要
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製品名
Anti-SOX22 antibody [86C2a] -
製品の詳細
Mouse monoclonal [86C2a] to SOX22 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Recombinant fragment -
免疫原
SOX22 recombinant fragment (Human)
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 1% BSA, 0.03% Potassium phosphate, 0.812% Sodium chloride, 0.1312% Sodium phosphate, 0.0225% Potassium chloride, PBS -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
ab54371 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane. -
ポリ/モノ
モノクローナル -
クローン名
86C2a -
アイソタイプ
IgG2a -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab54371の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use at an assay dependent concentration. Detects a band of approximately 30 kDa (predicted molecular weight: 34 kDa).
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特記事項 |
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WB
Use at an assay dependent concentration. Detects a band of approximately 30 kDa (predicted molecular weight: 34 kDa). |
ターゲット情報
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機能
Binds to the sequence 5'-AACAAT-3'. -
組織特異性
Expressed most abundantly in the CNS. Also expressed in fetal brain and kidney and adult heart, pancreas, testis and ovary. Other tissues were only weakly positive. -
配列類似性
Contains 1 HMG box DNA-binding domain. -
細胞内局在
Nucleus. - Information by UniProt
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別名
- Homo sapiens SRY (sex determining region Y) box 12 antibody
- Protein SOX-22 antibody
- SOX 12 antibody
see all
画像
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Anti-SOX22 antibody [86C2a] (ab54371) + immunised recombinant protein
Predicted band size: 34 kDa
Observed band size: 30 kDa why is the actual band size different from the predicted?
データシートおよび資料
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Datasheet download
参考文献 (4)
ab54371 は 4 報の論文で使用されています。
- Zhai D et al. LncRNA LGALS8-AS1 Promotes Breast Cancer Metastasis Through miR-125b-5p/SOX12 Feedback Regulatory Network. Front Oncol 11:711684 (2021). PubMed: 34745940
- Wei L et al. TMPO-AS1, a Novel E2F1-Regulated lncRNA, Contributes to the Proliferation of Lung Adenocarcinoma Cells via Modulating miR-326/SOX12 Axis. Cancer Manag Res 12:12403-12414 (2020). PubMed: 33293866
- Du F et al. Sex determining region Y-box 12 (SOX12) promotes gastric cancer metastasis by upregulating MMP7 and IGF1. Cancer Lett 452:103-118 (2019). PubMed: 30922917
- Zhang W et al. MicroRNA-744 inhibits migration and invasion of hepatocellular carcinoma cells by targeting SOX12. Oncol Rep 40:3585-3592 (2018). PubMed: 30542724