Anti-SKIP 抗体 (ab67715)
Key features and details
- Mouse polyclonal to SKIP
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-SKIP antibody -
製品の詳細
Mouse polyclonal to SKIP -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein within Human SKIP aa 1-450. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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ポジティブ・コントロール
- Transfected 293T cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.4
Constituent: PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab67715の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
1/500 - 1/1000. Predicted molecular weight: 51 kDa.
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特記事項 |
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WB
1/500 - 1/1000. Predicted molecular weight: 51 kDa. |
ターゲット情報
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機能
Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-triphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate. May negatively regulate assembly of the actin cytoskeleton. -
組織特異性
Ubiquitously expressed with highest levels in skeletal muscle, heart and kidney. -
配列類似性
Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family. -
細胞内局在
Endoplasmic reticulum. Following stimulation with EGF, translocates to membrane ruffles. - Information by UniProt
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参照データベース
- Entrez Gene: 51763 Human
- Omim: 607875 Human
- SwissProt: Q9BT40 Human
- Unigene: 632238 Human
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別名
- 43 kDa form skeletal muscle and kidney enriched inositol phosphatase antibody
- Inositol polyphosphate 5-phosphatase K antibody
- INP5K_HUMAN antibody
see all
画像
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All lanes : Anti-SKIP antibody (ab67715) at 1/500 dilution
Lane 1 : SKIP transfected 293T cell lysate
Lane 2 : non transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 51 kDa
Observed band size: 51 kDa
データシートおよび資料
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Datasheet download
参考文献 (1)
ab67715 は 1 報の論文で使用されています。
- Wu MY et al. SNW1 is a critical regulator of spatial BMP activity, neural plate border formation, and neural crest specification in vertebrate embryos. PLoS Biol 9:e1000593 (2011). WB . PubMed: 21358802