Anti-S100A12/CGRP 抗体 (ab37657)
Key features and details
- Rabbit polyclonal to S100A12/CGRP
- Suitable for: IHC-Fr, WB
- Reacts with: Human, Recombinant fragment
- Isotype: IgG
製品の概要
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製品名
Anti-S100A12/CGRP antibody
S100A12/CGRP 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to S100A12/CGRP -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Fr, WBmore details -
種交差性
交差種: Human, Recombinant fragment -
免疫原
Fusion protein corresponding to Human S100A12/CGRP.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.1% Sodium azide
Constituents: 50% Glycerol, PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab37657の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-Fr |
1/2000.
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WB |
1/1000 - 1/10000. Detects a band of approximately 10.5 kDa (predicted molecular weight: 10.5 kDa).
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特記事項 |
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IHC-Fr
1/2000. |
WB
1/1000 - 1/10000. Detects a band of approximately 10.5 kDa (predicted molecular weight: 10.5 kDa). |
ターゲット情報
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機能
Calcitermin possesses antifungal activity against C.albicans and is also active against E.coli and P.aeruginosa but not L.monocytogenes and S.aureus. Binds calcium, zinc and copper. Presence of zinc increases the affinity for calcium. Plays an important role in the inflammatory response. Interaction with AGER on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. -
組織特異性
Monocytes and lymphocytes. -
配列類似性
Belongs to the S-101 family.
Contains 2 EF-hand domains. - Information by UniProt
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参照データベース
- Entrez Gene: 6283 Human
- Omim: 603112 Human
- SwissProt: P80511 Human
- Unigene: 19413 Human
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別名
- CAAF1 antibody
- CAGC antibody
- Calcitermin antibody
see all
画像
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Anti-S100A12/CGRP antibody (ab37657) detects macrophage infiltrates expressing S100A12/CGRP in colon tissues from a patient with Crohn’s disease.
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Anti-S100A12/CGRP antibody (ab37657) + 200 ng recombinant human S100A12/CGRP
Secondary
anti-rabbit IgG alkalind phosphatase conjugate
Predicted band size: 10.5 kDa
Observed band size: 10.5 kDa
Additional bands at: 21 kDa (possible dimer)
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (11)
ab37657 は 11 報の論文で使用されています。
- Zhang J et al. The Causal Role of Magnesium Deficiency in the Neuroinflammation, Pain Hypersensitivity and Memory/Emotional Deficits in Ovariectomized and Aged Female Mice. J Inflamm Res 14:6633-6656 (2021). PubMed: 34908863
- Zeng Z et al. Expression, Location, Clinical Implication, and Bioinformatics Analysis of RNASET2 in Gastric Adenocarcinoma. Front Oncol 10:836 (2020). PubMed: 32528897
- Wang Q et al. Quantitative proteomic analysis of urinary exosomes in kidney stone patients. Transl Androl Urol 9:1572-1584 (2020). PubMed: 32944520
- Wu DM et al. S100A9 gene silencing inhibits the release of pro-inflammatory cytokines by blocking the IL-17 signalling pathway in mice with acute pancreatitis. J Cell Mol Med 22:2378-2389 (2018). WB ; Mouse . PubMed: 29441717
- Bouvet GF et al. DNA Methylation Regulates RGS2-induced S100A12 Expression in Airway Epithelial Cells. Am J Respir Cell Mol Biol 59:601-613 (2018). PubMed: 29944393