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Product name
RuBi-Glutamate
Description
Novel caged-glutamate compound, uncaged by visible light
Biological description
Novel caged-glutamate compound based on ruthenium photochemistry. Excited with visible wavelengths and releases glutamate after one- or two-photon excitation. It has high quantum efficiency and can be used at low concentrations. Enables the photoactivation of neuronal dendrites and circuits with visible or two-photon light sources, achieving single cell, or even single spine, precision.
General notes
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
RuBi-Glutamate is light senstive and it is recommended that the compound is protected from light.
Sold under license from Columbia University; Patent Pending
Properties
Chemical name
(Bis(2,2'-bipyridine-N,N')trimethylphosphine)-(S)-1-aminopropane-1,3-dicarboxylic acid ruthenium(2+) complex sodium hexafluorophosphate salt
Molecular Weight
803.59
Chemical structure
Molecular formula
C28H33N5O4PRu.NaPF6
Solubility
Soluble in water to 20 mM
Storage instructions
Store at -20°C (desiccating conditions).
Research areas
Biochemicals >> Pharmacology >> Receptors & Transporters >> Glutamate >> Broad spectrum / non-selective >> Agonists
Biochemicals >> Chemical Type >> Caged Compounds
Biochemicals >> Chemical Type >> Biochemicals
Biochemicals >> Chemical Type >> Amino Acid
Biochemicals >> Product Range >> Just Add Water
References for RuBi-Glutamate (ab120408)
This product has been referenced in:
- Salierno M et al. A fast ruthenium polypyridine cage complex photoreleases glutamate with visible or IR light in one and two photon regimes. J Inorg Biochem 104:418-22 (2010).Read more (PubMed: 20060592) »
- Fino E et al. RuBi-Glutamate: Two-Photon and Visible-Light Photoactivation of Neurons and Dendritic spines. Front Neural Circuits 3:2 (2009).Read more (PubMed: 19506708) »
See all 2 publications for this product
Publishing research using ab120408? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"