RuBi-GABA, caged-GABA compound (ab120409)
Key features and details
- Novel caged-GABA compound, uncaged by visible light
- CAS Number: 1028141-88-9
- Soluble in DMSO to 25 mM. For water solubility, please refer to Guideline for Use Information Sheet
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
RuBi-GABA, caged-GABA compound -
製品の詳細
Novel caged-GABA compound, uncaged by visible light -
特記事項
RuBi-GABA is light sensitive and it is recommended that the compound is protected from light.
Sold under license from Columbia University; Patent Pending -
CAS 番号
1028141-88-9 -
構造式
製品の特性
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体系名
(Bis(2,2'-bipyridine-N,N')triphenylphosphine)-4-aminobutyric acid ruthenium hexafluorophosphate complex -
分子量
922.80 -
分子式
C42H39N5O2PRu.PF6 -
PubChem 登録番号
129316180 -
保存方法
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
溶解性
Soluble in DMSO to 25 mM. For water solubility, please refer to Guideline for Use Information Sheet -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
[F-].FP(F)(F)(F)F.[O-]C(=O)CCC[NH2+][Ru]36(n1ccccc1c2ccccn23)(n4ccccc4c5ccccn56)P(c7ccccc7)(c8ccccc8)c9ccccc9 -
由来
Synthetic
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研究分野
参考文献 (5)
ab120409 は 5 報の論文で使用されています。
- Goutierre M et al. KCC2 Regulates Neuronal Excitability and Hippocampal Activity via Interaction with Task-3 Channels. Cell Rep 28:91-103.e7 (2019). PubMed: 31269453
- Imbriglio T et al. Developmental abnormalities in cortical GABAergic system in mice lacking mGlu3 metabotropic glutamate receptors. FASEB J 33:14204-14220 (2019). PubMed: 31665922
- Lin WC et al. A Comprehensive Optogenetic Pharmacology Toolkit for In Vivo Control of GABA(A) Receptors and Synaptic Inhibition. Neuron 88:879-891 (2015). PubMed: 26606997
- Zayat L et al. Ruthenium polypyridyl phototriggers: from beginnings to perspectives. Philos Trans A Math Phys Eng Sci 371:20120330 (2013). PubMed: 23776299
- Gauvain G et al. The neuronal K-Cl cotransporter KCC2 influences postsynaptic AMPA receptor content and lateral diffusion in dendritic spines. Proc Natl Acad Sci U S A 108:15474-9 (2011). PubMed: 21878564