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RuBi-4AP

Product code: ab120410 (formerly Asc-410)

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Overview

Product name

RuBi-4AP

Description

Caged K+ channel blocker, uncaged by visible light

Biological description

Water soluble caged 4-aminopyridine (4-AP) based on ruthenium photochemistry. Excited by visible wavelengths and has two-photon uncaging capabilities under physiological conditions. Releases voltage-dependent K+ channel blocker 4-aminopyridine (ab120122) when uncaged.

General notes

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

RuBi-4AP is light senstive and it is recommended that the compound is protected from light.

Sold under license from Columbia University; Patent Pending

Properties

Chemical name

Bis(2,2'-bipyridine-N,N')bis(4-aminopyridine-N1) ruthenium(2+) dichloride complex

Molecular Weight

672.58

Chemical structure

Chemical Structure

Molecular formula

C30H28Cl2N8Ru

Storage instructions

Store at -20°C (desiccating conditions).

Research areas

Biochemicals >> Pharmacology >> Ion Channels >> Potassium >> Blockers
Biochemicals >> Chemical Type >> Caged Compounds
Biochemicals >> Chemical Type >> Biochemicals

References for RuBi-4AP (ab120410)

This product has been referenced in:

See all 4 publications for this product

Publishing research using ab120410? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"