FITC Anti-Rhodopsin 抗体 [4D2] (ab183399)
Key features and details
- FITC Mouse monoclonal [4D2] to Rhodopsin
- Suitable for: ELISA
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
製品の概要
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製品名
FITC Anti-Rhodopsin antibody [4D2]
Rhodopsin 一次抗体 製品一覧 -
製品の詳細
FITC Mouse monoclonal [4D2] to Rhodopsin -
由来種
Mouse -
標識
FITC. Ex: 493nm, Em: 528nm -
アプリケーション
適用あり: ELISAmore details -
種交差性
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免疫原
Recombinant fragment corresponding to Bovine Rhodopsin (N terminal).
Database link: P02699 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Store In the Dark. -
バッファー
Preservative: 0.09% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
4D2 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Isotype control
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab183399の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ELISA |
Use at an assay dependent concentration.
|
特記事項 |
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ELISA
Use at an assay dependent concentration. |
ターゲット情報
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機能
Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal. -
組織特異性
Rod shaped photoreceptor cells which mediates vision in dim light. -
関連疾患
Retinitis pigmentosa 4
Night blindness, congenital stationary, autosomal dominant 1 -
配列類似性
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. -
翻訳後修飾
Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
Contains one covalently linked retinal chromophore. -
細胞内局在
Membrane. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia. - Information by UniProt
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別名
- CSNBAD1 antibody
- MGC138309 antibody
- MGC138311 antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab183399 は 3 報の論文で使用されています。
- Zhao Q et al. Comparative Transcriptome Profiling of the Loaches Triplophysa bleekeri and Triplophysa rosa Reveals Potential Mechanisms of Eye Degeneration. Front Genet 10:1334 (2019). PubMed: 32010191
- Liu F et al. Pathogenic mutations in retinitis pigmentosa 2 predominantly result in loss of RP2 protein stability in humans and zebrafish. J Biol Chem 292:6225-6239 (2017). PubMed: 28209709
- Liu F et al. Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish. Hum Mol Genet 24:4648-59 (2015). PubMed: 26034134