Rhodadyn™ C10, cell-permeable dynamin I inhibitor (ab120795)
Key features and details
- Highly potent cell-permeable dynamin I inhibitor
- CAS Number: 1367579-04-1
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Rhodadyn™ C10, cell-permeable dynamin I inhibitor -
製品の詳細
Highly potent cell-permeable dynamin I inhibitor -
生理活性の詳細
Highly potent cell-permeable dynamin I GTPase activity inhibitor (IC50 values are 7.1 and 30.3 μM at dynamin I and dynamin II, respectively). Blocks clathrin-mediated endocytosis of transferrin when applied for 30 minutes to U2OS cells in culture (IC50 = 7.0 μM).
Rhodadyn™ B10 negative control also available (ab120796).
Robertson J et al. The rhodadyn™ a new class of small molecule inhibitors of dynamin GTPase. ACS Med. Chem (2012). -
精製度
> 98% -
特記事項
Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovations Ltd. Rhodadyn™ is a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd. -
CAS 番号
1367579-04-1 -
構造式
製品の特性
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体系名
(5Z)-5-[4-[3-(Dimethylamino)propoxy]benzylidene]-3-ethyl-2-thioxo-1,3-thiazolidin-4-one -
分子量
350.49 -
分子式
C17H22N2O2S2 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM -
使用に関する注意
Unstable; make up solutions fresh and use immediately.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (0)
ab120795 は論文での使用が確認できていません。