Recombinant human FKBP2 protein (ab93681)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
製品の詳細
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製品名
Recombinant human FKBP2 protein
FKBP2 タンパク質・ペプチド 製品一覧 -
生理活性
Specific activity is > 700nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmol of suc-AAPF-pNA per minute at 37°C in Tris-HCl pH 8.0 using chymotrypsin.
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精製度
> 90 % SDS-PAGE.
ab93681 is purified using conventional chromatography techniques. -
発現系
Escherichia coli -
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSL PQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK IPGGATLVFEVELLKIERRTEL
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特性
Our Abpromise guarantee covers the use of ab93681 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Functional Studies
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on Dry Ice. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.0154% DTT, 0.242% Tris, 10% Glycerol (glycerin, glycerine)This product is an active protein and may elicit a biological response in vivo, handle with caution.
関連情報
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別名
- 13 kDa FK506-binding protein
- 13 kDa FKBP
- EC 5.2.1.8
see all -
機能
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. -
組織特異性
T-cells and thymus. -
配列類似性
Belongs to the FKBP-type PPIase family. FKBP2 subfamily.
Contains 1 PPIase FKBP-type domain. -
細胞内局在
Endoplasmic reticulum membrane. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab93681 は 2 報の論文で使用されています。
- Yoshikawa N et al. Role of FK506 Binding Protein on Tacrolimus Distribution in Red Blood Cells. Pharm Res 37:143 (2020). PubMed: 32661607
- Bielecka MK et al. Recombinant protein truncation strategy for inducing bactericidal antibodies to the macrophage infectivity potentiator protein of Neisseria meningitidis and circumventing potential cross-reactivity with human FK506-binding proteins. Infect Immun 83:730-42 (2015). PubMed: 25452551