製品の概要

  • 製品名
    Recombinant Human RGS19 protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMPTPHEAEKQITGPEEADRPPSMSSHDTAS PAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPS PEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEA NQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDA QLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
    • 分子量
      27 kDa including tags
    • 領域
      1 to 217
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab101949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 90 % SDS-PAGE.
    ab101949 is purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, PBS, pH 7.4

関連情報

  • 別名
    • G alpha interacting protein
    • G protein signalling regulator 19
    • G protein, alpha-interacting protein
    • G-alpha-interacting protein
    • GAIP
    • GNAI3IP
    • Guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein
    • Regulator of G protein signalling 19
    • Regulator of G-protein signaling 19
    • RGS19
    • RGS19_HUMAN
    • RGSGAIP
    see all
  • 機能
    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
  • 組織特異性
    Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.
  • 配列類似性
    Contains 1 RGS domain.
  • 翻訳後修飾
    Fatty acylated. Heavily palmitoylated in the cysteine string motif.
    Phosphorylated, mainly on serine residues.
  • 細胞内局在
    Membrane.
  • Information by UniProt

画像

  • 15% SDS-PAGE analysis of 3µg ab101949.

参考文献

ab101949 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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