Recombinant Human Profilin 1 protein (ab87760)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Suitable for: SDS-PAGE
製品の詳細
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製品名
Recombinant Human Profilin 1 protein
Profilin 1 タンパク質・ペプチド 製品一覧 -
精製度
> 95 % SDS-PAGE.
ab87760 is purified using conventional chromatography techniques. -
発現系
Escherichia coli -
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MAGWNAYIDN LMADGTCQDA AIVGYKDSPS VWAAVPGKTF VNITPAEVGV LVGKDRSSFY VNGLTLGGQK CSVIRDSLLQ DGEFSMDLRT KSTGGAPTFN VTVTKTDKTL VLLMGKEGVH GGLINKKCYE MASHLRRSQY
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab87760 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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製品の状態
Liquid -
備考
Endotoxin level: < 1.0 EU per 1 µg of protein (determined by LAL method). -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.316% Tris HCl, 10% Glycerol
関連情報
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別名
- Actin binding protein
- ALS18
- Epididymis tissue protein Li 184a
see all -
機能
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. -
配列類似性
Belongs to the profilin family. -
細胞内局在
Cytoplasm > cytoskeleton. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (6)
ab87760 は 6 報の論文で使用されています。
- Ramírez de Mingo D et al. Conformational dynamics in the disordered region of human CPEB3 linked to memory consolidation. BMC Biol 20:129 (2022). PubMed: 35658951
- Allen A et al. Actin-binding protein profilin1 promotes aggressiveness of clear-cell renal cell carcinoma cells. J Biol Chem 295:15636-15649 (2020). PubMed: 32883810
- George L et al. Profilin-1 is dysregulated in endometroid (type I) endometrial cancer promoting cell proliferation and inhibiting pro-inflammatory cytokine production. Biochem Biophys Res Commun 531:459-464 (2020). PubMed: 32800551
- Menkhorst EM et al. Invasive trophoblast promote stromal fibroblast decidualization via Profilin 1 and ALOX5. Sci Rep 7:8690 (2017). PubMed: 28821715
- Zienkiewicz A et al. Chip-based capillary electrophoresis profiling of olive pollen extracts used for allergy diagnosis and immunotherapy. Electrophoresis 35:2681-5 (2014). PubMed: 24888349
- Caglayan E et al. Profilin-1 is expressed in human atherosclerotic plaques and induces atherogenic effects on vascular smooth muscle cells. PLoS One 5:e13608 (2010). PubMed: 21049052