製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      SLTIAEFKCKLELLVGSPASCMELELYGVDDKFYSKLDQEDALLGSYPVD DGCRIHVIDHSGARLGEYEDVSRVEKYTISQEAYDQRQDTVRSFLKRSKL
    • 分子量
      37 kDa including tags
    • 領域
      31 to 130

特性

Our Abpromise guarantee covers the use of ab117056 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

    ELISA

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • CG22
    • CKAPI
    • Cytoskeleton associated protein 1
    • Cytoskeleton associated protein CKAPI
    • Cytoskeleton-associated protein 1
    • Cytoskeleton-associated protein CKAPI
    • Tbcb
    • TBCB_HUMAN
    • Tubulin folding cofactor B
    • Tubulin specific chaperone B
    • Tubulin-folding cofactor B
    • Tubulin-specific chaperone B
    see all
  • 機能
    Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.
  • 組織特異性
    Found in most tissues.
  • 配列類似性
    Belongs to the TBCB family.
    Contains 1 CAP-Gly domain.
  • 翻訳後修飾
    Phosphorylation by PAK1 is required for normal function. Phosphorylated upon DNA damage, probably by ATM or ATR.
    Ubiquitinated in the presence of GAN which targets it for degradation by the proteasome.
  • 細胞内局在
    Cytoplasm. Cytoplasm > cytoskeleton. Colocalizes with microtubules. In differentiated neurons, located in the cytoplasm. In differentiating neurons, accumulates at the growth cone.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE showing ab117056 at approximately 36.63 kDa.
    Stained with Coomassie Blue.

参考文献

ab117056 has not yet been referenced specifically in any publications.

レビューと Q&A

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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