製品の概要

法規制情報

製品の詳細

  • 由来
    Recombinant
  • 由来
    Baculovirus infected Sf9 cells
  • アミノ酸配列
    • 生物種
      Human

特性

Our Abpromise guarantee covers the use of ab71474 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Sodium chloride, 50mM Tris HCl, 0.25mM DTT, 0.1mM PMSF, pH 7.5

関連情報

  • 別名
    • CDI1
    • Cdk associated protein phosphatase
    • CDK2 associated dual specificity phosphatase
    • CDK2-associated dual-specificity phosphatase
    • CDKN3
    • CDKN3_HUMAN
    • CIP2
    • Cyclin dependent kinase inhibitor 3
    • Cyclin dependent kinase interacting protein 2
    • Cyclin dependent kinase interactor 1
    • Cyclin-dependent kinase inhibitor 3
    • Cyclin-dependent kinase interactor 1
    • Cyclin-dependent kinase-interacting protein 2
    • FLJ25787
    • KAP
    • KAP1
    • Kinase associated phosphatase
    • Kinase-associated phosphatase
    • MGC70625
    • OTTHUMP00000178991
    see all
  • 機能
    May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner.
  • 関連疾患
    Defects in CDKN3 are found in patients with hepatocellular carcinoma (HCC) [MIM:114550].
  • 配列類似性
    Belongs to the protein-tyrosine phosphatase family.
  • 細胞内局在
    Cytoplasm > perinuclear region.
  • Information by UniProt

画像

  • SDS-PAGE showing ab71474 at approximately 51kDa.

参考文献

ab71474 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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