Anti-PEBP4 抗体 (ab99468)
Key features and details
- Goat polyclonal to PEBP4
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-PEBP4 antibody -
製品の詳細
Goat polyclonal to PEBP4 -
由来種
Goat -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide within Human PEBP4 aa 200-300 (C terminal). The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. NP_659399.2
Database link: Q96S96 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris buffered saline -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab99468 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab99468の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 26 kDa.
A 1 hour primary incubation is recommended for this product. An additional band of unknown identity was also consistently observed at 30kDa. This band was successfully blocked by incubation with the immunizing peptide. |
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IHC-P |
Use at an assay dependent concentration.
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特記事項 |
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WB
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 26 kDa. A 1 hour primary incubation is recommended for this product. An additional band of unknown identity was also consistently observed at 30kDa. This band was successfully blocked by incubation with the immunizing peptide. |
IHC-P
Use at an assay dependent concentration. |
ターゲット情報
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関連性
PEBP4 appears to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization. -
細胞内局在
Lysosome -
参照データベース
- Entrez Gene: 157310 Human
- Omim: 612473 Human
- SwissProt: Q96S96 Human
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別名
- 1700051A02Rik antibody
- 1700081D17Rik antibody
- AI429082 antibody
see all
画像
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (2)
ab99468 は 2 報の論文で使用されています。
- Li H et al. Phosphatidylethanolamine-binding protein 4 is associated with breast cancer metastasis through Src-mediated Akt tyrosine phosphorylation. Oncogene N/A:N/A (2013). IHC-P ; Human . PubMed: 24276246
- Yu GP et al. The expression of PEBP4 protein in lung squamous cell carcinoma. Tumour Biol 32:1257-63 (2011). WB, IHC-P ; Human . PubMed: 21887552