Anti-PDE3B 抗体 [SMCP3B] (ab95814)
Key features and details
- Rat monoclonal [SMCP3B] to PDE3B
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG2a
製品の概要
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製品名
Anti-PDE3B antibody [SMCP3B]
PDE3B 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [SMCP3B] to PDE3B -
由来種
Rat -
特異性
ab95814 is specific to PDE3B. It does not react with PDE3A. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse
非交差種: Human -
免疫原
Recombinant fragment, corresponding to C terminal amino acids 643-1100 of Mouse PDE3B expressed in E. coli.
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ポジティブ・コントロール
- Mouse heart lysate; Mouse lymph node cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: 2.68% PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
SMCP3B -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab95814の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 124 kDa.
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特記事項 |
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WB
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 124 kDa. |
ターゲット情報
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機能
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. -
組織特異性
Abundant in adipose tissues. -
配列類似性
Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 18576 Mouse
- SwissProt: Q61409 Mouse
- Unigene: 430730 Mouse
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別名
- 5''-cyclic phosphodiesterase B antibody
- Adipocyte cAMP phosphodiesterase cGMP inhibited antibody
- AI847709 antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (1)
ab95814 は 1 報の論文で使用されています。
- Vang AG et al. Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac. Biochem J 456:463-73 (2013). PubMed: 24007532