Anti-Neuroligin 2 抗体 (ab36602)
Key features and details
- Rabbit polyclonal to Neuroligin 2
- Suitable for: ELISA
- Isotype: IgG
製品の概要
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製品名
Anti-Neuroligin 2 antibody
Neuroligin 2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Neuroligin 2This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »
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由来種
Rabbit -
種交差性
交差が予測される動物種: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to Human Neuroligin 2 aa 650-750 conjugated to keyhole limpet haemocyanin.
(Peptide available asab36601) -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use
アプリケーション | Abreviews | 特記事項 |
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ELISA |
Use at an assay dependent concentration. This antibody gave a positive result in ELISA against the immunizing peptide (ab36601).
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特記事項 |
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ELISA
Use at an assay dependent concentration. This antibody gave a positive result in ELISA against the immunizing peptide (ab36601). |
ターゲット情報
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関連性
Neuroligins are cell adhesion proteins that are thought to instruct the formation and alignment of synaptic specializations. The three known rodent neuroligin isoforms share homologous extracellular acetylcholinesterase-like domains that bridge the synaptic cleft and bind beta-neurexins. All neuroligins have identical intracellular C-terminal motifs that bind to PDZ domains of various target proteins. Neuroligin 2 is exclusively localized to inhibitory synapses in rat brain and dissociated neurons. In immature neurons, neuroligin 2 is found at synapses and also at GABAA receptor aggregates that are not facing presynaptic termini. -
細胞内局在
Cell Membrane -
参照データベース
- Entrez Gene: 57555 Human
- Entrez Gene: 216856 Mouse
- Entrez Gene: 117096 Rat
- Omim: 606479 Human
- SwissProt: Q8NFZ4 Human
- SwissProt: Q69ZK9 Mouse
- SwissProt: Q62888 Rat
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別名
- KIAA1366 antibody
- MGC67386 antibody
- NL2 antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab36602 は 2 報の論文で使用されています。
- Heshmati M et al. Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility. Proc Natl Acad Sci U S A 115:1111-1116 (2018). PubMed: 29339486
- Swaminathan A et al. Non-canonical mTOR-Independent Role of DEPDC5 in Regulating GABAergic Network Development. Curr Biol 28:1924-1937.e5 (2018). PubMed: 29861134