Anti-NPEPPS 抗体 (ab77643)
Key features and details
- Goat polyclonal to NPEPPS
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-NPEPPS antibody
NPEPPS 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to NPEPPS -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Horse, Cow, Dog, Xenopus laevis, Chimpanzee, Macaque monkey -
免疫原
Synthetic peptide:
C-KRDAESIHQYLLQRK
, corresponding to C terminal amino acids 899-913 of Human NPEPPS (NP_006301.3) -
ポジティブ・コントロール
- Human Brain (Cerebral Cortex) lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris buffered saline -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab77643の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
特記事項 |
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WB: Use at a concentration of 0.2 - 0.5 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 103 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能
Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain. -
組織特異性
Detected in liver, epithelium of renal tubules, epithelium of small and large intestine, gastric epithelial cells, and alveoli of the lung (at protein level). -
配列類似性
Belongs to the peptidase M1 family. -
細胞内局在
Cytoplasm > cytosol. Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 9520 Human
- Entrez Gene: 19155 Mouse
- Entrez Gene: 50558 Rat
- Omim: 606793 Human
- SwissProt: P55786 Human
- SwissProt: Q11011 Mouse
- Unigene: 443837 Human
- Unigene: 29824 Mouse
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別名
- AAP-S antibody
- Aminopeptidase puromycin sensitive antibody
- Cytosol alanyl aminopeptidase antibody
see all
画像
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Anti-NPEPPS antibody (ab77643) at 0.3 µg/ml + Human cerebral cortex lysate in RIPA buffer at 35 µg
Predicted band size: 103 kDa
Observed band size: 110 kDa why is the actual band size different from the predicted?
データシートおよび資料
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Datasheet download
参考文献 (0)
ab77643 は論文での使用が確認できていません。