Anti-Mephalan 抗体 [MP5/73] (ab97892)
Key features and details
- Rat monoclonal [MP5/73] to Mephalan
- Suitable for: ELISA
- Reacts with: Species independent
- Isotype: IgG2b
製品の概要
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製品名
Anti-Mephalan antibody [MP5/73] -
製品の詳細
Rat monoclonal [MP5/73] to Mephalan -
由来種
Rat -
特異性
This antibody was developed to improve detection of melphalan-DNA adducts through its ability to recognise the stabilised adduct. This antibodiy can be used for quantification of melphalan adducts in purified DNA by ELISA and for immunofluorescent detection of melphalan-DNA adducts in single cells. -
アプリケーション
適用あり: ELISAmore details -
種交差性
交差種: Species independent -
免疫原
Full length native protein (purified) corresponding to Mephalan.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
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精製度
Protein A/G purified -
ポリ/モノ
モノクローナル -
クローン名
MP5/73 -
ミエローマ
Y3/Ag1.2.3 -
アイソタイプ
IgG2b -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab97892の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
Use at an assay dependent dilution.
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特記事項 |
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ELISA
Use at an assay dependent dilution. |
ターゲット情報
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関連性
Mephalan hydrochloride is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab97892 は 3 報の論文で使用されています。
- Rothbarth J et al. Immunohistochemical detection of melphalan-DNA adducts in colon cancer cells in vitro and human colorectal liver tumours in vivo. Biochem Pharmacol 67:1771-8 (2004). PubMed: 15081876
- Frank AJ & Tilby MJ Quantification of DNA adducts in individual cells by immunofluorescence: effects of variation in DNA conformation. Exp Cell Res 283:127-34 (2003). PubMed: 12581733
- Tilby MJ et al. Immunological detection of DNA damage caused by melphalan using monoclonal antibodies. Cancer Res 47:1542-6 (1987). PubMed: 3815354