Anti-MTMR6 抗体 (ab69875)
Key features and details
- Mouse polyclonal to MTMR6
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-MTMR6 antibody
MTMR6 一次抗体 製品一覧 -
製品の詳細
Mouse polyclonal to MTMR6 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein within Human MTMR6. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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ポジティブ・コントロール
- MTMR6 transfected 293T cell lysate and human kidney tissue lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab69875の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/1000. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa).
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特記事項 |
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WB
1/500 - 1/1000. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa). |
ターゲット情報
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機能
Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells. -
組織特異性
Expressed in CD4+ T-cells. -
配列類似性
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
Contains 1 myotubularin phosphatase domain. -
細胞内局在
Nucleus envelope. - Information by UniProt
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参照データベース
- Entrez Gene: 9107 Human
- Omim: 603561 Human
- SwissProt: Q9Y217 Human
- Unigene: 643702 Human
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別名
- 4022440C11Rik antibody
- AI428804 antibody
- AU041072 antibody
see all
画像
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Anti-MTMR6 antibody (ab69875) at 1/500 dilution + human kidney tissue lysate at 50 µg
Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 72 kDa
Observed band size: 72 kDa -
All lanes : Anti-MTMR6 antibody (ab69875) at 1/500 dilution
Lane 1 : MTMR6 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 72 kDa
Observed band size: 72 kDa
データシートおよび資料
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Datasheet download
参考文献 (1)
ab69875 は 1 報の論文で使用されています。
- Campa CC et al. Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes. Nat Chem Biol N/A:N/A (2018). PubMed: 29915378