Biotin Anti-MHC class II I E kappa 抗体 [14-4-4S] (ab93504)
Key features and details
- Biotin Mouse monoclonal [14-4-4S] to MHC class II I E kappa
- Suitable for: Flow Cyt
- Reacts with: Mouse, Rat
- Conjugation: Biotin
- Isotype: IgG2a
Related conjugates and formulations
製品の概要
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製品名
Biotin Anti-MHC class II I E kappa antibody [14-4-4S]
MHC class II I E kappa 一次抗体 製品一覧 -
製品の詳細
Biotin Mouse monoclonal [14-4-4S] to MHC class II I E kappa -
由来種
Mouse -
標識
Biotin -
特異性
ab93504 reacts with the mouse and rat MHC Class II, I-E subregion-encoded glycoprotein in mice strains of H-2k, H-2d, H-2p and H-2r. H-2f and H-2s haplotypes do not express the I-E antigen. -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Mouse, Rat -
免疫原
This product was produced with the following immunogens:
Tissue, cells or virus corresponding to Mouse MHC class II I E kappa. C3H mouse skin graft
Tissue, cells or virus corresponding to Mouse MHC class II I E kappa. Mouse splenocytes -
ポジティブ・コントロール
- Mouse splenocytes
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特記事項
The 14-4-4S monoclonal antibody has been reported to block antigen presentation in in vitro assays.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, PBS -
Concentration information loading...
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精製度
Protein G purified -
一次抗体 備考
The 14-4-4S monoclonal antibody has been reported to block antigen presentation in in vitro assays. -
ポリ/モノ
モノクローナル -
クローン名
14-4-4S -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab93504の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
ab18454 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
特記事項 |
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Flow Cyt
Use at an assay dependent concentration. ab18454 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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関連性
A major histocompatibility complex class II receptor. These display processed antigens from virally infected or transformed cells. Class II positive cells ('antigen presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re export the peptides (now bound to MHC class II protein) to the cell surface. These peptide MHC class II complexes can then be recognized by specific CD4+ lymphocytes. -
細胞内局在
Type I membrane protein -
別名
- H2 Ea antibody
- H2-Ea antibody
データシートおよび資料
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Datasheet download
参考文献 (4)
ab93504 は 4 報の論文で使用されています。
- Spencer JS et al. Expression and function of mixed isotype MHC class II molecules in normal mice. J Immunol 151:6822-32 (1993). PubMed: 8258692
- Pruitt SK et al. The effect of xenoreactive antibody and B cell depletion on hyperacute rejection of guinea pig-to-rat cardiac xenografts. Transplantation 56:1318-24 (1993). PubMed: 8278996
- Liu H et al. Immune T cells sorted by flow cytometry confer protection against infection with Treponema pallidum subsp. pertenue in hamsters. Infect Immun 58:1685-90 (1990). PubMed: 2187804
- Maloy WL et al. Evidence for the association of I-A and I-E molecules in d-haplotype mice. Mol Immunol 23:263-9 (1986). PubMed: 3459016