Anti-MEX3A 抗体 (ab79046)
Key features and details
- Rabbit polyclonal to MEX3A
- Suitable for: IHC-P, ICC/IF, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-MEX3A antibody -
製品の詳細
Rabbit polyclonal to MEX3A -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, ICC/IF, WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human MEX3A (C terminal). The immunogen is located within amino acids 420 - 470 of MEX3A. .
Database link: A1L020 -
ポジティブ・コントロール
- WB: SK-N-SH cell lysate IHC-P: Human brain tissue. ICC/IF: Human brain tissue.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
-
精製度
Immunogen affinity purified -
特記事項(精製)
Affinity chromatography purified via peptide column -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab79046の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-P |
Use at an assay dependent concentration.
|
|
ICC/IF |
Use a concentration of 20 µg/ml.
|
|
WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 54 kDa.
|
特記事項 |
---|
IHC-P
Use at an assay dependent concentration. |
ICC/IF
Use a concentration of 20 µg/ml. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 54 kDa. |
ターゲット情報
-
関連性
RNA binding protein, may be involved in post transcriptional regulatory mechanisms. -
細胞内局在
Cytoplasmic and Nuclear. Note: Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. -
参照データベース
- Entrez Gene: 92312 Human
- Omim: 611007 Human
- SwissProt: A1L020 Human
-
別名
- Mex3 homolog A (C. elegans) antibody
- MEX3A protein antibody
- Ring finger and KH domain containing 4 antibody
see all
画像
-
Immunofluorescence of MEX3A in Human brain tissue with ab79046 at 20 ug/mL.
-
Immunohistochemistry of Human brain tissue using ab79046 at 2.5 μg/mL.
-
All lanes : Anti-MEX3A antibody (ab79046) at 1 µg/ml
Lane 1 : SK-N-SH cell lysate
Lane 2 : SK-N-SH cell lysate with blocking peptide
Lysates/proteins at 15 µg per lane.
Predicted band size: 54 kDa
Observed band size: 64 kDa why is the actual band size different from the predicted?
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (14)
ab79046 は 14 報の論文で使用されています。
- Tsang SM et al. Sox11 regulates mammary tumour-initiating and metastatic capacity in Brca1-deficient mouse mammary tumour cells. Dis Model Mech 14:N/A (2021). PubMed: 33969421
- Liu Y et al. Discovery of key genes as novel biomarkers specifically associated with HPV-negative cervical cancer. Mol Ther Methods Clin Dev 21:492-506 (2021). PubMed: 33997099
- Zhang P et al. Comprehensive Analysis of Prognostic Value of MEX3A and Its Relationship with Immune Infiltrates in Ovarian Cancer. J Immunol Res 2021:5574176 (2021). PubMed: 34189143
- Li H et al. Mex3a promotes oncogenesis through the RAP1/MAPK signaling pathway in colorectal cancer and is inhibited by hsa-miR-6887-3p. Cancer Commun (Lond) 41:472-491 (2021). PubMed: 33638620
- Yan L et al. Mex-3 RNA binding MEX3A promotes the proliferation and migration of breast cancer cells via regulating RhoA/ROCK1/LIMK1 signaling pathway. Bioengineered 12:5850-5858 (2021). PubMed: 34486491