Anti-MARVELD1 抗体 (ab91640)
Key features and details
- Rabbit polyclonal to MARVELD1
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-MARVELD1 antibody -
製品の詳細
Rabbit polyclonal to MARVELD1 -
由来種
Rabbit -
特異性
Specific for MARVELD1. Does not bind to other MARVELD proteins. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse -
免疫原
16 amino acids synthetic peptide from the N terminal region of Human MARVELD1 (EAW49903).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab91640の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 19 kDa.
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特記事項 |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 19 kDa. |
ターゲット情報
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機能
Microtubule-associated protein that exhibits cell cycle-dependent localization and can inhibit cell proliferation and migration. -
組織特異性
Widely expressed in normal tissues. Down-regulated in multiple primary tumors. -
配列類似性
Contains 1 MARVEL domain. -
細胞内局在
Cell membrane. Cytoplasm > cytoskeleton. Nucleus. Observed in the nucleus and at the perinuclear region during interphase, but localizes at the mitotic spindle and midbody at metaphase. A significant fraction of MARVELD1 translocates to the plasma membrane during anaphase or upon microtubule depolymerization. - Information by UniProt
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参照データベース
- Entrez Gene: 277010 Mouse
- SwissProt: Q7TQJ1 Mouse
- Unigene: 206250 Mouse
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別名
- GB14 antibody
- MALD1_HUMAN antibody
- MARVD1 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (7)
ab91640 は 7 報の論文で使用されています。
- Ma W et al. MARVELD1 attenuates arsenic trioxide-induced apoptosis in liver cancer cells by inhibiting reactive oxygen species production. Ann Transl Med 7:200 (2019). PubMed: 31205918
- Zhang C et al. MARVELD1 interacting with catalase regulates reactive oxygen species metabolism and mediates the sensitivity to chemotherapeutic drugs in epithelial tumors of the reproductive system. Mol Carcinog 58:1410-1426 (2019). PubMed: 31066116
- Liu W et al. MARVELD1 depletion leads to dysfunction of motor and cognition via regulating glia-dependent neuronal migration during brain development. Cell Death Dis 9:999 (2018). PubMed: 30250269
- Chen Y et al. The depletion of MARVELD1 leads to murine placenta accreta via integrin β4-dependent trophoblast cell invasion. J Cell Physiol 233:2257-2269 (2018). PubMed: 28708243
- Yao Y et al. MARVELD1 modulates cell surface morphology and suppresses epithelial-mesenchymal transition in non-small cell lung cancer. Mol Carcinog 55:1714-1727 (2016). PubMed: 26509557
- Wieczfinska J et al. The whole-genome expression analysis of peripheral blood mononuclear cells from aspirin sensitive asthmatics versus aspirin tolerant patients and healthy donors after in vitro aspirin challenge. Respir Res 16:147 (2015). WB . PubMed: 26646719
- Hu J et al. MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1. PLoS One 8:e68291 (2013). WB ; Human . PubMed: 23826386