Anti-Lass5 抗体 (ab73289)
Key features and details
- Rabbit polyclonal to Lass5
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-Lass5 antibody
Lass5 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Lass5 -
由来種
Rabbit -
特異性
ab73289 may cross-react with the highly homologous Lass6. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat -
免疫原
An 18 amino acid peptide near the amino terminus of human Lass5
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ポジティブ・コントロール
- WB: Rat brain tissue lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab73289の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa).
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特記事項 |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa). |
ターゲット情報
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機能
May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner. -
配列類似性
Contains 1 homeobox DNA-binding domain.
Contains 1 TLC (TRAM/LAG1/CLN8) domain. -
細胞内局在
Nucleus membrane. Endoplasmic reticulum membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 366984 Rat
- SwissProt: B2RYI9 Rat
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別名
- CerS5 antibody
- FLJ25304 antibody
- LAG1 homolog ceramide synthase 5 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab73289 は 3 報の論文で使用されています。
- Pani T et al. Alternative splicing of ceramide synthase 2 alters levels of specific ceramides and modulates cancer cell proliferation and migration in Luminal B breast cancer subtype. Cell Death Dis 12:171 (2021). PubMed: 33568634
- Markowski AR et al. Ceramides Profile Identifies Patients with More Advanced Stages of Colorectal Cancer. Biomolecules 10:N/A (2020). PubMed: 32325909
- Ji R et al. Increased de novo ceramide synthesis and accumulation in failing myocardium. JCI Insight 2:N/A (2017). WB ; Human . PubMed: 28469091