Anti-Lactoferrin 抗体 (ab112968)
Key features and details
- Goat polyclonal to Lactoferrin
- Suitable for: ELISA
- Reacts with: Cow
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Lactoferrin antibody
Lactoferrin 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to Lactoferrin -
由来種
Goat -
アプリケーション
適用あり: ELISAmore details -
種交差性
交差種: Cow -
免疫原
Full length native protein (purified) corresponding to Cow Lactoferrin. bovine milk origin
Database link: P24627 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 6.8
Preservative: 0.09% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
Antiserum was solid phase adsorbed to ensure specificity. ab112968 was isolated by affinity chromatography using antigen coupled to agarose beads. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab112968の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ELISA |
Use at an assay dependent concentration.
Coating: Use 1/100-1/500 dilution; Primary: Use 1/1000-1/30000 dilution. |
特記事項 |
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ELISA
Use at an assay dependent concentration. Coating: Use 1/100-1/500 dilution; Primary: Use 1/1000-1/30000 dilution. |
ターゲット情報
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機能
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.
Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration.
Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors.
The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. -
配列類似性
Belongs to the transferrin family.
Contains 2 transferrin-like domains. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 280846 Cow
- SwissProt: P24627 Cow
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別名
- GIG12 antibody
- Growth inhibiting protein 12 antibody
- HLF2 antibody
see all
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (3)
ab112968 は 3 報の論文で使用されています。
- Santos-Pereira C et al. Lactoferrin perturbs lipid rafts and requires integrity of Pma1p-lipid rafts association to exert its antifungal activity against Saccharomyces cerevisiae. Int J Biol Macromol 171:343-357 (2021). PubMed: 33421469
- Peng Z et al. Autophagy Induced by Palmitic Acid Regulates Neutrophil Adhesion Through the Granule-Dependent Degradation of αMβ2 Integrin in Dairy Cows With Fatty Liver. Front Immunol 12:726829 (2021). PubMed: 34691032
- Zhang SD et al. Differential proteomic profiling of endometrium and plasma indicate the importance of hydrolysis in bovine endometritis. J Dairy Sci 100:9324-9337 (2017). PubMed: 28918157